首页|TCI给药与恒速给药在胸科手术麻醉维持中的效果比较

TCI给药与恒速给药在胸科手术麻醉维持中的效果比较

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目的 探究靶控输注(TCI)给药方式与恒速给药方式在胸科手术麻醉维持中的效果。方法 70 例于本院行开胸手术的患者,以随机数字表法分为观察组与对照组,各 35 例。对照组以恒速给药方式进行麻醉维持,观察组以TCI给药方式进行麻醉维持。比较两组不同时间点[麻醉前(T0)、插管后(T1)、手术开始时(T2)、手术结束时(T3)]血流动力学指标[心率(HR)、平均动脉压(MAP)、血氧饱和度(SpO2)]、苏醒时间、麻醉药物用量、并发症发生情况。结果 结果 对照组T1、T2、T3 时HR低于本组T0,T2 时HR低于本组T1、T3 时(P<0。05);对照组T1、T2 时MAP低于本组T0、T3 时,T3时MAP高于本组T0 时(P<0。05);对照组T1、T3 时SpO2 均低于本组T0、T2 时(P<0。05)。观察组T1 时MAP均高于本组T0、T2、T3 时,T2 时MAP均低于本组T0、T3 时(P<0。05);观察组T0、T1、T2、T3时HR、SpO2 水平比较,差异无统计学意义(P>0。05)。与对照组比较,观察组变化趋势更平稳。观察组苏醒时间(8。49±2。11)min短于对照组的(12。54±2。06)min,麻醉药物使用量(1223。06±40。29)mg少于对照组的(1268。57±56。71)mg,差异均有统计学意义(P<0。05)。观察组并发症发生率 5。71%低于对照组的22。86%,差异有统计学意义(P<0。05)。结论 在对患者进行开胸手术的过程中,使用TCI给药方式进行麻醉维持效果较好。
Comparison of effect of TCI administration and constant rate administration in maintenance of anesthesia in thoracic surgery
Objective To investigate the effect of target controlled infusion(TCI)administration and constant rate administration in maintenance of anesthesia in thoracic surgery.Methods A total of 70 patients who underwent thoracotomy in our hospital were divided into an observation group and a control group according to random number table,with 35 cases in each group.The control group maintained anesthesia by constant rate administration,and the observation group maintained anesthesia by TCI administration.The hemodynamic indexes[heart rate(HR),mean arterial pressure(MAP),and blood oxygen saturation(SpO2)]at different time points[before anesthesia(T0),after intubation(T1),at the beginning of surgery(T2),at the end of surgery(T3)],recovery time,anesthetic dosage and occurrence of complications were compared between the two groups.Results HR at T1,T2 and T3 of the control group was lower than that of this group at T0,and HR at T2 was lower than that of this group at T1 and T3(P<0.05).MAP at T1 and T2 in the control group was lower than those at T0 and T3 in this group,and MAP at T3 was higher than that at T0 in this group(P<0.05).SpO2 at T1 and T3 in the control group were lower than those at T0 and T2 in this group(P<0.05).MAP at T1 of the observation group were higher than that of this group at T0,T2 and T3,and MAP at T2 were lower than that of this group at T0 and T3(P<0.05).Comparison of HR and SpO2 levels at T0,T1,T2 and T3 of the observation group,the difference was not statistically significant(P>0.05).Compared with the control group,the change trend of observation group was more stable.The recovery time of(8.49±2.11)min in the observation group was shorter than(12.54±2.06)min in the control group,and the anesthetic dosage of(1223.06±40.29)mg was less than(1268.57±56.71)mg in the control group.The difference was statistically significant(P<0.05).The complication rate of the observation group was 5.71%,which was lower than 22.86%of the control group,and the difference was statistically significant(P<0.05).Conclusion In the process of thoracotomy,the anesthesia maintenance effect of TCI administration is better.

ThoracotomyAnesthesiaTarget-controlled administrationConstant rate administrationHemodynamics

刘丽、张辉、周月兰

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412205 湖南省胸科医院麻醉科

开胸手术 麻醉 靶控给药 恒速给药 血流动力学

2024

中国现代药物应用
中国水利电力医学科学技术学会

中国现代药物应用

影响因子:0.862
ISSN:1673-9523
年,卷(期):2024.18(5)
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