首页|自拟理胃汤治疗肝郁脾虚型功能性消化不良的临床疗效观察

自拟理胃汤治疗肝郁脾虚型功能性消化不良的临床疗效观察

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目的 通过自拟理胃汤治疗肝郁脾虚型功能性消化不良患者,观察其临床治疗效果。方法 55 例肝郁脾虚型功能性消化不良患者,随机分为观察组(27 例)和对照组(28 例)。对照组给予多潘立酮治疗,观察组给予自拟理胃汤加减治疗。比较两组临床疗效,治疗后中、西医症状评分,治疗后心理及生活质量评分。结果 治疗后,观察组的总有效率 96。30%较对照组的 78。57%显著升高,差异有统计学意义(P<0。05)。治疗后,观察组的胃脘胀满、两胁胀满、叹息纳差、餐后饱胀不适、上腹痛、上腹烧灼感评分分别为(1。86±0。13)、(1。77±0。12)、(2。03±0。04)、(1。98±0。11)、(1。92±0。06)、(2。15±0。14)分,较对照组的(2。15±0。14)、(2。05±0。12)、(2。19±0。03)、(2。15±0。14)、(2。17±0。05)、(2。36±0。13)分显著降低,差异有统计学意义(P<0。05)。观察组的焦虑评分(61。74±5。57)分、抑郁评分(60。96±6。35)分较对照组的(66。37±8。64)、(68。96±7。60)分显著降低,生活质量评分(98。46±1。76)分较对照组的(76。41±1。82)分显著升高,差异有统计学意义(P<0。05)。结论 采用自拟理胃汤治疗肝郁脾虚型功能性消化不良患者,可以显著改善患者的中、西医症状,缓解患者焦虑、抑郁的心理状态,改善消化不良,提高总体生活质量,疗效确切,可以在临床推广使用。
Observation on clinical efficacy of functional dyspepsia of liver-depression and spleen-deficiency type treated with self-made Liwei decoction
Objective To observe the clinical effect of self-made Liwei decoction in the treatment of patients with functional dyspepsia of liver-depression and spleen-deficiency type.Methods A total of 55 patients with functional dyspepsia of liver-depression and spleen-deficiency type were randomly divided into an observation group(27 cases)and a control group(28 cases).The control group was treated with domperidone,while the observation group was treated with modified self-made Liwei decoction.The clinical efficacy,scores of symptoms of traditional Chinese and Western medicine,psychological and quality of life scores after treatment were compared between the two groups.Results After treatment,the total effective rate of 96.30%in the observation group was significantly higher than 78.57%in the control group,and the difference was statistically significant(P<0.05).After treatment,the scores of epigastric fullness,bilateral fullness,poor appetite,postprandial fullness and discomfort,epigastric pain,and epigastric burning sensation in the observation group were(1.86±0.13),(1.77±0.12),(2.03±0.04),(1.98±0.11),(1.92±0.06)and(2.15±0.14)points,which were significantly lower than(2.15±0.14),(2.05±0.12),(2.19±0.03),(2.15±0.14),(2.17±0.05)and(2.36±0.13)points in the control group.The difference was statistically significant(P<0.05).The anxiety score of(61.74±5.57)points and depression score of(60.96±6.35)points in the observation group were significantly lower than(66.37±8.64)and(68.96±7.60)points in the control group;the quality of life score of(98.46±1.76)points in the observation group was significantly higher than(76.41±1.82)points in the control group;the difference was statistically significant(P<0.05).Conclusion The treatment of functional dyspepsia of liver-depression and spleen-deficiency type with modified Liwei decoction can improve the symptoms of traditional Chinese and Western medicine,relieve the psychological state of anxiety and depression,improve dyspepsia,improve the overall quality of life,and has definite curative effect.It can be widely promoted in clinical practice.

Self-made Liwei decoctionLiver-depression and spleen-deficiency typeFunctional dyspepsiaClinical study

孙晓鹏、贾淑兰

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118000 丹东市中医院脾胃病科

自拟理胃汤 肝郁脾虚型 功能性消化不良 临床研究

2024

中国现代药物应用
中国水利电力医学科学技术学会

中国现代药物应用

影响因子:0.862
ISSN:1673-9523
年,卷(期):2024.18(5)
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