Research progress of dexmedetomidine in surgical anesthesia and analgesia
With the economic development of our country,people have changed greatly on the material and spiritual level,which has also caused changes in their tolerance to pain.When patients go to see a doctor,most of them hope that doctors can try to reduce the pain or even make it painless.Therefore,clinical anesthesia has been widely developed under this promotion.Effective anesthesia can significantly reduce the pain of patients,so as to make the treatment proceed more smoothly,and ultimately greatly improve the treatment efficiency.Dexmedetomidine is a novel α2-adrenergic receptor agonist with high clinical application and good effect.Its affinity is 8 times that of clonidine.Dexmedetomidine plays an important role in analgesia,sedation,anti-stress and other aspects,and can also reduce the dosage of other such drugs and reduce the incidence of adverse reactions.Therefore,it has been widely used in laboratory experiments,and has achieved good results.In recent years,dexmedetomidine has been more and more used in cardiovascular surgery anesthesia,which has received good effects in sedation,analgesia,anti-sympathetic,inhibition of stress response,stability of hemodynamics and other aspects.Therefore,this article reviews the research progress of its pharmacology,pharmacodynamics and clinical application,in order to provide theoretical basis and foundation for clinical anesthesia.
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维普
