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生化检验指标对病毒性肝炎的诊断价值分析

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目的 分析生化检验指标在病毒性肝炎诊断中的应用价值。方法 择取 60 例病毒性肝炎患者作为研究组,另选择进行常规检查的健康体检者 60 例作为健康组。两组均进行生化指标检验,比较两组受检者血常规指标[白细胞计数(WBC)、血小板计数(PLT)、淋巴细胞百分比(LYMPH)及中性粒细胞百分比(GRAN)]、肝功能指标[谷丙转氨酶(ALT)、白蛋白(ALB)、血清总胆红素(TBIL)及白蛋白与球蛋白比值(A/G)]、肝功能指标[ALT、谷草转氨酶(AST)、TBIL、血清胆碱酯酶(CHE)]升高情况、血清蛋白质指标[总蛋白(TP)、球蛋白(GLO)]。结果 研究组WBC(5。01±1。79)×109/L、PLT(108。79±72。45)×109/L及GRAN(54。72±12。38)%低于健康组的(6。92±1。43)×109/L、(175。84±43。61)×109/L、(62。94±8。71)%,LYMPH(37。21±11。85)%高于健康组的(29。59±5。43)%(P<0。05)。研究组ALT(95。32±34。96)U/L、TBIL(24。79±10。74)μmol/L高于健康组的(28。67±17。34)U/L、(14。83±8。25)μmol/L,ALB(37。96±4。83)g/L、A/G(1。13±0。21)低于健康组的(46。78±3。24)g/L、(1。65±0。32)(P<0。05)。研究组ALT、AST、TBIL及CHE升高占比分别为 81。67%、86。67%、91。67%、88。33%,高于健康组的 11。67%、16。67%、21。67%、6。67%(P<0。05)。研究组TP(47。24±3。10)g/L低于健康组的(68。39±3。26)g/L,GLO(36。17±1。32)g/L高于健康组的(32。34±1。06)g/L(P<0。05)。结论 病毒性肝炎患者的血常规指标、肝功能指标测定值与健康人群相比存在显著差异,肝功能指标升高占比明显高于健康人群,能够为患者疾病的诊断和临床疗效的评估提供可靠的参考依据,可以在病毒性肝炎的诊断中推广使用。
Analysis of the value of biochemical test indicators in the diagnosis of viral hepatitis
Objective To analyze the value of biochemical test indicators in the diagnosis of viral hepatitis.Methods A total of 60 patients with viral hepatitis were selected as the study group,and 60 healthy subjects who underwent routine examination were selected as the healthy group.Biochemical indicators were tested in both groups.Both groups were compared in terms of blood routine indicators[white blood cell count(WBC),platelet count(PLT),lymphocyte percentage(LYMPH)and neutrophilic granulocyte percentage(GRAN)],liver function indicators[alanine aminotrasferase(ALT),albumin(ALB),serum total bilirubin(TBIL)and albumin and globulin ratio(A/G)]and elevated liver function indicators[ALT,aspartate transaminase(AST),TBIL,serum cholinesterase(CHE)and serum protein indicators[total protein(TP),globulin(GLO)].Results The study group had WBC of(5.01±1.79)×109/L,PLT of(108.79±72.45)×109/L and GRAN of(54.72±12.38)%,which were lower than(6.92±1.43)×109/L,(175.84±43.61)×109/L and(62.94±8.71)%in the healthy group;the study group had higher LYMPH of(37.21±11.85)%than(29.59±5.43)%in the healthy group(P<0.05).The study group had ALT of(95.32±34.96)U/L and TBIL of(24.79±10.74)μmol/L,which were higher than(28.67±17.34)U/L and(14.83±8.25)μmol/L in the healthy group;the study group had ALB of(37.96±4.83)g/L and A/G of(1.13±0.21),which were lower than(46.78±3.24)g/L and(1.65±0.32)in the healthy group(P<0.05).The percentage of elevated ALT,AST,TBIL and CHE in the study group were 81.67%,86.67%,91.67%and 88.33%,which were higher than 11.67%,16.67%,21.67%and 6.67%in the healthy group(P<0.05).The study group had lower TP of(47.24±3.10)g/L than(68.39±3.26)g/L in healthy group,and higher GLO of(36.17±1.32)g/L than(32.34±1.06)g/L in healthy group(P<0.05).Conclusion The blood routine indicators and liver function indicators of patients with viral hepatitis are significantly different from those of the healthy population,and the percentage of elevated liver function indicators is significantly higher than that of the healthy population,which can provide a reliable reference basis for the diagnosis of the patients'diseases and the evaluation of clinical efficacy,and can be popularized for use in the clinical diagnosis of viral hepatitis.

Biochemical test indicatorsViral hepatitisDiagnostic characteristicsClinical value

伍彩霞

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511540 广东省清远市清城区龙塘镇卫生院检验科

生化检验指标 病毒性肝炎 诊断特点 临床价值

2024

中国现代药物应用
中国水利电力医学科学技术学会

中国现代药物应用

影响因子:0.862
ISSN:1673-9523
年,卷(期):2024.18(6)
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