The diagnostic significance of non-invasive indicators for ulcerative colitis
Objective To study the practical value of non-invasive indicators for ulcerative colitis(UC).Methods 66 patients with UC were selected as the study group and 66 healthy subjects were selected as the control group.The blood indicators[neutrophil to lymphocyte ratio(NLR),platelet to lymphocyte ratio(PLR),neutrophil to platelet ratio(NPR),monocyte to lymphocyte ratio(MLR),total bilirubin(TBIL),indirect bilirubin(IBIL),serum amyloid A(SAA)]and fecal indicators[fecal calcarein(FC),fecal lactoferrin(FL)]of the two groups were detected and compared.Results The study group had NLR of(3.54±1.02),PLR of(223.39±45.27),NPR of(15.01±4.28),SAA of(22.60±5.08)mg/L,TBIL of(19.03±7.56)μmol/L,IBIL of(10.39±3.09)μmol/L,FC of(177.24±21.27)μg/g,and FL of(201.72±32.11)μg/g,which were higher than(1.54±0.68),(75.35±22.21),(8.11±2.99),(3.89±1.32)mg/L,(15.01±7.31)μmol/L,(7.43±2.81)μmol/L,(32.42±13.71)μg/g,and(55.00±17.50)μg/g in the control group(P<0.05).There was no difference in MLR between the study group and the control group(P>0.05).The moderate group had NLR of(3.99±1.13),PLR of(247.56±80.39),SAA of(33.76±11.04)mg/L,FC of(279.48±104.63)μg/g,and which were higher than(3.08±1.02),(199.21±78.25),(11.43±5.30)mg/L,(75.00±23.14)μg/g,and(125.39±31.77)μg/g in mild group(P<0.05).There were no differences in NPR,MLR,TBIL and IBIL between moderate group and mild group(P>0.05).NLR,PLR,NPR,SAA,TBIL,IBIL,FC,and FL were the influencing factors for the onset of UC(P<0.05),and NLR,SAA,and FC were the influencing factors for the severity of UC(P<0.05).Conclusion The use of non-invasive indicators in the diagnosis of UC is helpful in assessing treatment effectiveness and predicting disease recurrence at any time.
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