首页|输尿管置管联合钬激光碎石治疗输尿管中下段结石合并前列腺增生的效果及对性功能的影响

输尿管置管联合钬激光碎石治疗输尿管中下段结石合并前列腺增生的效果及对性功能的影响

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目的 研究输尿管置管联合钬激光碎石治疗输尿管中下段结石合并前列腺增生的效果及对性功能的影响。方法 300例输尿管中下段结石合并前列腺增生患者,根据具体手术方式不同分为试验组(152例)和对照组(148例)。对照组给予钬激光碎石治疗,试验组给予输尿管置管联合钬激光碎石治疗。比较两组围术期情况、国际勃起功能指数 5(IIEF-5)评分、射精功能评分表(CIPE)评分、肾功能、临床改善情况及不良反应发生情况。结果 试验组失血量(82。34±28。56)ml少于对照组的(103。47±33。58)ml,手术时间(60。66±32。27)min、血尿时间(2。45±0。14)d及住院时间(8。51±0。77)d均短于对照组的(72。55±33。26)min、(3。56±1。10)d、(13。60±1。35)d(P<0。05)。术后,两组IIEF-5、CIPE评分均较术前升高,且试验组IIEF-5 评分(9。06±2。41)分、CIPE评分(28。04±3。31)分高于对照组的(8。04±2。25)、(25。16±3。24)分(P<0。05)。术后,两组血清肌酐(SCR)、尿白蛋白(ALB)、血尿素氮(BUN)水平均较术前降低,且试验组血清SCR(68。12±7。14)μmol/L、尿ALB(88。12±23。61)mg/L、BUN(4。19±0。78)mmol/L低于对照组的(75。25±7。32)μmol/L、(106。28±24。62)mg/L、(4。89±0。83)mmol/L(P<0。05)。试验组腰痛、膀胱刺激及尿路梗阻改善时间分别为(9。71±1。28)、(7。51±1。01)、(8。72±1。31)d,均显著短于对照组的(11。31±1。30)、(8。89±1。21)、(10。20±1。50)d(P<0。05)。治疗期间,两组不良反应发生率比较无差异(P>0。05)。结论 在输尿管中下段结石合并前列腺增生患者中应用输尿管置管联合钬激光碎石效果显著,可有效改善患者性功能水平。
Effect of ureteral catheterization combined with holmium laser lithotripsy in the treatment of middle and lower ureteral calculi with prostatic hyperplasia and its influence on sexual function
Objective To study the effect of ureteral catheterization combined with holmium laser lithotripsy in the treatment of middle and lower ureteral calculi with prostatic hyperplasia and its influence on sexual function.Methods 300 patients with middle and lower ureteral calculi with prostatic hyperplasia were divided into an experimental group(152 cases)and a control group(148 cases)according to different surgical methods.The control group was given holmium laser lithotripsy,and the experimental group was given ureteral catheterization combined with holmium laser lithotripsy.The perioperative conditions,international index of erectile function-5(IIEF-5)score,Chinese index of sexual function for premature ejaculation(CIPE)score,renal function,clinical improvement,and adverse reactions were compared between the two groups.Results The experimental group had less blood loss of(82.34±28.56)ml than(103.47±33.58)ml in the control group;the experimental group had operation time of(60.66±32.27)min,hematuria time of(2.45±0.14)d and hospital stay of(8.51±0.77)d,which were shorter than(72.55±33.26)min,(3.56±1.10)d and(13.60±1.35)d in the control group(P<0.05).After surgery,IIEF-5 and CIPE scores in both groups were higher than those before surgery;the experimental group had IIEF-5 score of(9.06±2.41)points and CIPE score of(28.04±3.31)points,which were higher than(8.04±2.25)and(25.16±3.24)points in the control group(P<0.05).After surgery,the serum creatinine(SCR),urinary albumin(ALB)and blood urea nitrogen(BUN)levels in both groups were lower than those before surgery;the experimental group had serum SCR of(68.12±7.14)μmol/L,urinary ALB of(88.12±23.61)mg/L and BUN of(4.19±0.78)mmol/L,which were lower than(75.25±7.32)μmol/L,(106.28±24.62)mg/L and(4.89±0.83)mmol/L in the control group(P<0.05).The improvement times of lumbago,bladder irritation and urinary obstruction in the experimental group were(9.71±1.28),(7.51±1.01)and(8.72±1.31)d,which were significantly shorter than(11.31±1.30),(8.89±1.21)and(10.20±1.50)d in the control group(P<0.05).During treatment,there was no difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Ureteral catheterization combined with holmium laser lithotripsy can effectively improve the sexual function of patients with middle and lower ureteral calculi with prostatic hyperplasia.

Ureteral catheterizationHolmium laser lithotripsyMiddle and lower ureteral calculiProstatic hyperplasiaSexual function

陈富源、李少鹏、林宗棋、余乐、蔡建通

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362700 石狮市医院泌尿外科

输尿管置管 钬激光碎石 输尿管中下段结石 前列腺增生 性功能

2024

中国现代药物应用
中国水利电力医学科学技术学会

中国现代药物应用

影响因子:0.862
ISSN:1673-9523
年,卷(期):2024.18(7)
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