Analysis of the clinical effect of modified Qingre Qushi Tongluo formula combined with conventional Western medicine on patients with acute gouty arthritis of dampness heat accumulation type
Objective To analyze the effect of modified Qingre Qushi Tongluo formula combined with conventional Western medicine on patients with acute gouty arthritis of dampness heat accumulation type.Methods 110 patients with acute gouty arthritis of dampness heat accumulation type were selected.According to different treatment methods,they were divided into a control group and an intervention group,with 55 cases in each group.The control group was given conventional Western medicine treatment,while the intervention group was treated with modified Qingre Qushi Tongluo formula based on the control group.The treatment efficacy,blood uric acid levels,traditional Chinese medicine symptom score,quality of life,adverse reactions and recurrence were compared between the two groups.Results The total effective rate of the intervention group was 96.36%,which was higher than 83.64%of the control group(P＜0.05).After 1,2 and 3 months of treatment,the serum uric acid level in both groups was lower than that before treatment(P＜0.05).After 3 months of treatment,the serum uric acid level in the intervention group was(355.47±42.38)μmol/L,which was lower than(387.24±47.65)μmol/L in the control group(P＜0.05).Compared with before treatment,the traditional Chinese medicine symptom score in both groups decreased significantly and the activities of daily living(ADL)score increased significantly after treatment(P＜0.05).After treatment,the intervention group had lower traditional Chinese medicine symptom score of(4.65±1.20)points than(5.27±1.49)points in the control group,and higher ADL score of(80.10±7.55)points than(77.26±6.36)points in the control group(P＜0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P＞0.05).After 3 months of follow-up,the recurrence rate in the intervention group was 7.27%,which was lower than 23.64%in the control group(P＜0.05).Conclusion The combination of modified Qingre Qushi Tongluo formula and conventional Western medicine has a better therapeutic effect on acute gouty arthritis of dampness heat accumulation type.It can significantly reduce blood uric acid levels and recurrence rate,improve traditional Chinese medicine symptoms and quality of life,and have fewer adverse reactions.It has promotion value.
Acute gouty arthritisDampness heat accumulation typeQingre Qushi Tongluo formulaIntegrated traditional Chinese and Western medicineBlood uric acid
NETL
NSTL
万方数据
维普
