Observation on the effect of thromboelastography-guided blood transfusion during the perioperative period of open-heart surgery
Objective To explore the practical effect of thromboelastography-guided blood transfusion during the perioperative period of open-heart surgery.Methods 65 patients undergoing open-heart surgery were selected as the subjects.They were divided into a control group(33 cases)and a study group(32 cases)by randomized controlled manner.The control group received blood transfusion guidance based on coagulation indicators,while the study group received thromboelastography-guided blood transfusion.Comparison was made on blood transfusion(platelet,autologous blood,fresh frozen plasma and red blood cell input),blood transfusion effect[hemoglobin level and platelet count increment at completion of surgery and the time of intensive care unit(ICU)transfer],clinical outcome(tracheal intubation time,hospitalization time,ICU stay and mortality)between the two groups.Results There was no significant difference in red blood cell input and autologous blood input between the two groups(P＞0.05).The platelet input and fresh frozen plasma input of the study group were(523.32±152.39)and(321.41±65.33)ml,which were lower than(655.11±187.48)and(375.52±71.74)ml of the control group(P＜0.05).There were no significant differences in the hemoglobin level and platelet count increment between the two groups at completion of surgery(P＞0.05).The study group had hemoglobin of(118.41±10.41)g/L and platelet count augmentation index of(13.90±2.01)%at the time of ICU transfer,which were higher than(105.41±9.19)g/L and(10.41±2.33)%in the control group(P＜0.05).There were no deaths in the study group,and 1 death in the control group,with a mortality rate of 3.03%.There was no difference between the two groups(P＞0.05).The study group had tracheal intubation time of(19.12±5.49)h,ICU stay of(21.06±4.55)h and hospitalization time of(16.42±4.35)d,which were shorter than(21.81±5.11)h,(23.96±5.02)h and(19.33±5.06)d in the control group(P＜0.05).Conclusion Implementing thromboelastography-guided blood transfusion during the perioperative period of open-heart surgery can reduce blood transfusion volume and improve blood transfusion effect;At the same time,it can also shorten the time of tracheal intubation,improve clinical prognosis,and is worth applying and promoting.
NETL
NSTL
万方数据
维普
