Efficacy observation of methylprednisolone sodium succinate in the treatment of Mycoplasma pneumoniae pneumonia in children
Objective To explore the efficacy of methylprednisolone sodium succinate in the treatment of Mycoplasma pneumoniae pneumonia in children.Methods A total of 150 pediatric patients with Mycoplasma pneumoniae pneumonia were selected.According to random numerical table,they were randomly divided into two groups:the control group(n=75,treated with conventional medication)and the observation group(n=75,treated with conventional medication plus methylprednisolone sodium succinate).The clinical efficacy,disappearance time of clinical symptoms(lung shadows,lung rales,cough,and fever),and the improvement of serum inflammatory factor[hypersensitive C-reactive protein(hs-CRP)]before and after treatment were compared between the two groups.Results After treatment,the total effective rate of the observation group was 100.00%,which was higher than 88.00%of the control group(P＜0.05).After treatment,the disappearance time of lung shadows,lung rales,cough,and fever in the observation group were(7.41±2.88),(8.11±2.65),(5.54±0.33)and(4.88±0.35)d,which were shorter than(10.22±3.32),(10.77±3.12),(7.82±0.45)and(6.49±0.51)d in the control group(P＜0.05).Before treatment,hs-CRP levels were compared between the two groups(P＞0.05).After treatment,the observation group had lower hs-CRP level of(13.23±0.33)mg/L than(22.39±1.44)mg/L in the control group(P＜0.05).Conclusion Methylprednisolone sodium succinate shows significant clinical effect on children with Mycoplasma pneumoniae pneumonia,which can significantly improve the clinical symptoms and lower the levels of serum inflammatory factors of children.The clinical application value is significant.
Methylprednisolone sodium succinateMycoplasma pneumoniae pneumonia in childrenSerum inflammatory factorsClinical efficacy
NETL
NSTL
万方数据
维普
