Study on value of bifidobacterium triple viable capsule in the treatment of chronic gastritis caused by Helicobacter pylori infection
Objective To analyze the value of bifidobacterium triple viable capsule in the treatment of chronic gastritis caused by Helicobacter pylori(Hp)infection.Methods 100 patients with chronic gastritis caused by Hp infection were divided into a control group(50 cases)and an intervention group(50 cases)according to different treatment plans.The control group received conventional quadruple therapy,while the intervention group was treated with bifidobacterium triple viable capsules on the basis of the control group.The treatment efficacy,serum inflammatory indicators[interleukin-6(IL-6),interleukin-8(IL-8),hypersensitive C-reactive protein(hs-CRP)],and occurrence of adverse drug reactions were compared between the two groups of patients.Results After treatment,the total effective rate of the intervention group was 96.00%,which was higher than 84.00%of the control group,and the difference was statistically significant(P＜0.05).In the intervention group,the serum IL-6,IL-8 and hs-CRP before treatment were(275.43±42.65)ng/L,(154.39±24.06)ng/L and(26.38±4.26)mg/L;after treatment,they were(116.37±20.35)ng/L,(46.75±6.33)ng/L and(12.85±2.79)mg/L.In the control group,the serum IL-6,IL-8 and hs-CRP before treatment were(278.06±44.71)ng/L,(152.73±25.78)ng/L and(27.43±4.45)mg/L;after treatment,they were(130.34±24.18)ng/L,(53.20±8.17)ng/L and(15.14±3.34)mg/L.Compared with before treatment,the serum levels of IL-6,IL-8 and hs-CRP in both groups decreased significantly after treatment,and the serum levels of IL-6,IL-8 and hs-CRP in the intervention group were lower than those in the control group after treatment(P＜0.05).Adverse reactions occurred in 4 patients(8.00%)in the intervention group and 6 patients(12.00%)in the control group,and there was no significant difference in the incidence of adverse reactions between groups(P＞0.05).Conclusion For patients with chronic gastritis caused by Hp infection,the combination of Bifidobacterium triple viable capsules has a better effect,can reduce inflammatory reactions in the body,and has high drug safety,which has promotion value.
NETL
NSTL
万方数据
维普
