Effective volume of 0.25%ropivacaine in ultrasound-guided intermediate cervical plexus block
Objective To investigate the effective volumes(EV)of 0.25%ropivacaine in ultrasound-guided intermediate cervical plexus block,specifically the 50%effective volume and the 95%effective volume.Methods 29 patients who underwent elective neck surgery and were selected,and 0.25%ropivacaine was used for ultrasound-guided intermediate cervical plexus block;if all the nociceptive sensations in the dermatomes belonging to the branches of the cervical plexus disappeared,it was regarded as a complete block(complete block group,14 cases);otherwise,it was regarded as an incomplete block(incomplete block group,15 cases).The block effect was recorded,and the effective volume of 0.25%ropivacaine used for ultrasound-guided intermediate cervical plexus block was analyzed;the general characteristics,volume of ropivacaine,occurrence of complications,and diaphragm excursion during deep breathing before and after block were compared between the complete block group and the incomplete block group.Results The 50%effective volume for ultrasound-guided intermediate cervical plexus block with 0.25%ropivacaine was found to be 10.3 ml[95%confidence interval(CI)=(7.7,13.5)ml],while the 95%effective volume was determined to be 15.6 ml[95%CI=(12.8,44.0)ml].There were no significant differences in age,gender,American Society of Anesthesiologists(ASA)grade,height,weight and body mass index(BMI)between the complete block group and the incomplete block group(P＞0.05).The volume of ropivacaine in the complete block group was(11.1±2.0)ml,which was significantly higher than(9.2±2.0)ml in the incomplete block group,and the difference was statistically significant(P＜0.05).Before block,the diaphragm excursion during deep breathing in incomplete block group and complete block group were(4.17±0.87)and(4.09±0.85)cm,and the difference was not statistically significant in comparison(P＞0.05).After block,the diaphragm excursion during deep breathing in incomplete block group and complete block group were(4.09±0.85)and(3.99±0.70)cm,and the difference was not statistically significant in comparison(P＞0.05).Among the patients with complete blocks,one developed hoarseness,whose administered volume was 14 ml,but there were no occurrences of phrenic nerve block,vagus nerve block,local anesthetic drug toxicity,Horner's sign,or hypoxemia in the remaining patients.Conclusion The 50%effective volume of 0.25%ropivacaine for ultrasound-guided intermediate cervical plexus block is 10.3 ml[95%CI=(7.7,13.5)ml],while the 95%effective volume is 15.6 ml[95%CI=(12.8,44.0)ml].
NETL
NSTL
万方数据
维普
