Analysis of the efficacy of quinolone antibiotics in the clinical treatment of gynecological pelvic inflammatory diseases
Objective To explore the effect of quinolone antibiotics in the clinical treatment of gynecological pelvic inflammatory diseases.Methods 60 patients with gynecological pelvic inflammatory disease were selected.They were divided into a control group and a study group by lottery method,with 30 patients in each group.The control group was treated with traditional Chinese patent medicines,and the study group was treated with quinolone antibiotics based on the control group.The symptoms and sign score,treatment effect,inflammatory factors[C-reactive protein(CRP),interleukin-1(IL-1),interleukin-6(IL-6),tumor necrosis factor-α(TNF-α)]of the two groups were compared.Results Before treatment,there were no differences in scores of high fever,abdominal pain,lower abdominal distension,urethral inflammation,abnormal leucorrhea,menstrual disorder,lethargy,fatigue and insomnia between the two groups(P>0.05).After treatment,the scores of high fever,abdominal pain,lower abdominal distension,urethral inflammation,abnormal leucorrhea,menstrual disorder,lethargy,fatigue and insomnia in the study group were lower than those in the control group,with a statistically significant difference(P<0.05).The total effective rate of the study group was 96.67%,which was higher than 76.67%of the control group(P<0.05).After treatment,the study group had CRP of(16.38±9.80)mg/L,IL-1 of(61.29±11.31)pg/ml,TNF-α of(39.42±10.75)pg/ml,and IL-6 of(63.47±10.25)pg/ml,which were lower than(23.77±9.45)mg/L,(72.37±11.20)pg/ml,(50.59±10.80)pg/ml,and(70.85±10.37)pg/ml in the control group,with a statistically significant difference(P<0.05).Conclusion The application of quinolone antibiotics in gynecological pelvic inflammatory diseases can improve the treatment effect,reduce the level of inflammatory factors,and improve the signs and symptoms.
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