Study on clinical effect of manual aspiration thrombectomy in the treatment of acute cerebral artery occlusion
Objective To observe the feasibility,safety and clinical efficacy of manual aspiration thrombectomy(MAT)in the treatment of acute cerebral artery occlusion.Methods Among 27 patients with acute artery occlusion treated with MAT for the first time,19 patients undergoing MAT were selected as MAT group and 8 patients who underwent MAT combined with stent thrombectomy as MAT+stent group.The gender,age,smoking,hypertension,diabetes,atrial fibrillation,hyperlipidemia,coronary heart disease,rheumatic heart disease,intravenous thrombolysis,site of thrombolysis,time from puncture to revasculation,modified thrombolysis in cerebral infarction(mTICI)grading,thrombus escape,cerebral hemorrhage,National Institutes of Health Stroke Scale(NIHSS)score before surgery,and NIHSS score 7 d after surgery,90-d modified Rankin scale(mRS)score≤2 points,and death were recorded in both groups.Results 27 patients underwent MAT for the first time,of which 16 cases(59.3%)were males and 40.7%were females,at(67.2±11.5)years of age;intravenous thrombolysis occurred in 9 cases(33.3%).thrombectomy sites were internal carotid artery in 5 cases(18.5%),middle cerebral artery in 18 cases(66.7%),basilar artery in 3 cases(11.1%),and posterior cerebral artery in 1 case(3.7%).The time from puncture to recanalization was 65(48,90)min.Vascular recanalization was achieved in 26 patients(96.3%).There were 12 cases(44.4%)with mTICI grade 2b and 14 cases(51.9%)with MTICI grade 3.Thrombus escape occurred in 5 cases(18.5%).Symptomatic intracerebral hemorrhage occurred in 2 cases(7.4%)and asymptomatic intracerebral hemorrhage occurred in 1 case(3.7%).The NIHSS score was(13.9±3.8)points before surgery,and(8.4±6.6)points at 7 d after surgery;NIHSS score at 7 d after surgery was lower than that before surgery(P<0.05).There were 14 cases(51.9%)with 90 d mRS score≤2 points;3 cases(11.1%)died,of which 2 cases were caused by symptomatic cerebral hemorrhage after thrombus extraction,and 1 case was caused by pulmonary embolism.Conclusion MAT is feasible,safe and effective in the treatment of acute cerebral artery occlusion.
万方数据
维普
