Clinical efficacy and safety analysis of staged incremental balloon dilation for the treatment of Budd Chiari syndrome with inferior vena cava thrombosis
Objective To explore the clinical efficacy and safety of staged incremental balloon dilation for the treatment of Budd Chiari syndrome(BCS)with inferior vena cava thrombosis.Methods 62 patients with BCS complicated with inferior vena cava thrombosis were treated with staged incremental balloon dilation surgery,and the treatment outcomes(success rate of balloon preopening,thrombolysis rate,complications,and death)were analyzed.The laboratory parameters[white blood cell count(WBC),red blood cell count(RBC),hemoglobin(Hb),albumin(ALB),platelet count(PLT),alanine aminotrasferase(ALT),aspartate transaminase(AST),alkaline phosphatase(ALP),direct bilirubin(DBil),total cholesterol(TC)and high density lipoprotein cholesterol(HDL-C)]were compared before and after surgery.Results Among the 62 patients,the success rate of balloon preopening was 98.39%(61/62),and 1 patient was unable to open due to repeated dilation of the long segment of the inferior vena cava due to occlusion;among them,25 cases of fresh thrombi were cleared after catheter thrombolysis,while the rest were old thrombi with a complete thrombolysis rate of 93.44%(57/61)within 1 month;all patients had no symptomatic pulmonary embolism or death cases during the perioperative period.After surgery,PLT and HDL-C were(131.65±37.02)×109/L and(1.15±0.21)mmol/L,which were higher than(108.94±46.36)×109/L and(0.93±0.28)mmol/L before surgery;while ALP and DBil were(88.19±40.63)U/L and(21.02±7.59)μmol/L,which were lower than(111.57±57.48)U/L and(24.89±9.98)μmol/L before surgery(P<0.05).There was no significant difference in WBC,RBC,Hb,ALB,ALT,AST,and TC before and after surgery(P>0.05).Conclusion The clinical efficacy of staged incremental balloon dilation in the treatment of BCS complicated with inferior vena cava thrombosis is significant.The success rate and thrombolysis rate of the surgery are high,and the incidence of complications is low.It can effectively regulate the levels of PLT,HDL-C,and has positive significance in improving prognosis.
万方数据
维普
