Analysis of the efficacy and safety of different blue light irradiation methods in the treatment of neonatal hyperbilirubinemia
Objective To compare the efficacy and safety of different blue light irradiation methods in the treatment of neonatal hyperbilirubinemia.Methods 108 cases of neonatal hyperbilirubinemia were divided into intermittent group and continuous group according to random number table method,each with 54 cases.The intermittent group received intermittent blue light irradiation,and the continuous group received continuous blue light irradiation.Both groups were compared in terms of serum total bilirubin levels,total lighting time,jaundice subsidence time,length of hospital stay,and incidence of adverse reactions.Results After 48 and 96 h of treatment,the serum total bilirubin levels in the intermittent group were(211.29±20.19)and(112.18±10.23)μmol/L,which were lower than(245.81±19.98)and(143.19±9.98)μmol/L in the continuous group(P<0.05).There was no significant difference in the jaundice subsidence time and length of hospital stay between the two groups(P>0.05).The total lighting time in the intermittent group was(3.02±0.51)d,which was significantly shorter than the continuous group's(4.20±0.65)d(P<0.05).The incidence of adverse events in the intermittent group was 5.56%(3/54),which was lower than the continuous group's 24.07%(13/54)(P<0.05).Conclusion In the treatment of neonates with hyperbilirubinemia,intermittent blue light irradiation is definitely effective and comparable to continuous blue light irradiation,but it has a significantly lower incidence rate of adverse reactions,which has the value of popularization.
Blue light irradiationHyperbilirubinemiaNeonatesLighting timeBilirubinSafety
万方数据
维普
