Effect of combined detection of glycosylated hemoglobin and glycosylated serum protein in the diagnosis of early gestational diabetes mellitus
Objective To analyze the analyze the diagnostic value of combined detection of glycosylated hemoglobin and glycosylated serum protein in the diagnosis of early gestational diabetes mellitus,so as to find effective indicators for detection of early gestational diabetes mellitus.Methods 198 cases of early gestational diabetes mellitus were selected as the experimental group,and 200 healthy pregnant women during the same period were selected as the control group.The glycosylated hemoglobin and glycosylated serum protein were detected in both groups.The positive rates of the two groups of pregnant women were compared,and the sensitivity,specificity and accuracy of the three detection methods were compared.Results The positive rates of glycosylated hemoglobin and glycosylated serum protein alone and in combination in the experimental group were 83.3%,86.9%,and 98.0%,which were significantly higher than 12.0%,8.0%,and 2.0%in the control group,and the differences were all statistically significant(P<0.05).The sensitivity,specificity,and accuracy of the combined detection were 98.0%,98.0%,and 98.0%,which were significantly higher than those of the glycosylated hemoglobin(83.3%,88.0%,and 85.7%)and the glycosylated serum protein(86.9%,92.0%,and 89.4%)alone.The differences were all statistically significant(P<0.05).Conclusion Gestational diabetes mellitus can be evaluated and diagnosed by combined detection of glycosylated hemoglobin and glycosylated serum protein at the early stage,which can significantly improve the diagnostic rate and has certain clinical value.
Glycosylated hemoglobinGlycosylated serum proteinEarly gestational diabetes mellitusDiagnostic value
万方数据
维普
