Analysis of the predictive value of ultrasound detection of sac bud difference combined with baseline thromboelastography indicators for early pregnancy outcome
Objective To analyze the predictive value of ultrasound detection of sac bud difference combined with baseline thromboelastography indicators for early pregnancy outcome.Methods 215 cases of early pregnant women were divided into the normal group(with a sac bud difference of 14-18 mm),the mild small gestational sac group(with a sac bud difference of 10-13 mm),and the moderate small gestational sac group(with a sac bud difference of 6-9 mm),severe small gestational sac group(with a sac bud difference of 4-5 mm)and small gestational sac absolute abortion group(with a sac bud difference of≤3 mm)according to the size of the gestational sac difference of pregnant women,with 190,15,10,8 and 2 cases in each group.Transvaginal ultrasound and thromboelastography were performed in all five groups of pregnant women to compare the detection results(normal pregnancy rate and abnormal abortion rate)and baseline thromboelastography indicators[reaction time(R)value,coagulation time(K)value,Angel Angle,maximum amplitude(MA)value,and comprehensive coagulation index(CI)value]for pregnant women with different sac bud difference.The predictive value of ultrasound detection for early pregnancy outcome was analyzed.Results The normal pregnancy rates of the normal group,mild small gestational sac group,moderate small gestational sac group,severe small gestational sac group and small gestational sac absolute abortion group were 93.33%,86.67%and 70.00,0,0,and the abnormal abortion rates were 6.67%,13.33%,30.00%,100.00%,and 100.00%.There were significant differences in pregnancy outcomes among the five groups(P<0.05).215 cases of early pregnant women were followed up,with 204 cases of normal pregnancy and 11 cases of abnormal miscarriage;ultrasound detected 188 cases of normal pregnancy and 27 cases of abnormal miscarriage.The sensitivity of ultrasound detection for pregnancy outcome of early pregnant women was 89.22%(182/204),the specificity was 45.45%(5/11),the positive predictive value was 96.81%(182/188),and the negative predictive value was 18.52%(5/27),and the accuracy reached 86.98%(187/215).There were significant differences in R value,K value,Angel Angle,MA value and CI value among the five groups(P<0.05).The R and K values in descending order were normal group,mild small gestational sac group,moderate small gestational sac group,severe small gestational sac group and small gestational sac absolute abortion group,whereas the Angel angle,MA and CI values in descending order were in the opposite order to the above.Conclusion Sac bud difference is related to pregnancy outcome.Either too large or too small will lead to miscarriage.Ultrasound detection can effectively predict the risk of miscarriage.Baseline thromboelastography can be used to evaluate the coagulation status of pregnant women and guide clinical anticoagulation treatment.
万方数据
维普
