Comparison of the muscle relaxant effect of mivacurium chloride and cis-atracurium in corrective surgery for strabismus in children
Objective To compare the muscle relaxant effect of mivacurium chloride and cis-atracurium in corrective surgery for strabismus in children.Methods 80 children proposed for strabismus corrective surgery were randomly divided into a mivacurium chloride group(group M)and cis-atracurium group(group C),with 40 cases in each group.Group M was treated with mivacurium chloride during the anesthesia induction period,and group C was treated with cis-atracurium during the anesthesia induction period.Both groups were compared in terms of success rate of one-time laryngeal mask placement,duration of muscle relaxation,recovery time of muscle relaxation,time of laryngeal mask removal,use of muscle relaxation antagonists,length of recovery room stay,and occurrence of perioperative adverse events.Results There was no significant difference in the success rate of one-time laryngeal mask placement between the two groups(P>0.05).Group M had duration of muscle relaxation of(14.5±2.8)min,recovery time of muscle relaxation of(5.6±1.8)min,and length of recovery room stay of(19.4±3.7)min,which were obviously shorter than(27.8±2.1),(9.8±2.1)and(26.6±4.2)min in group C;group M had significantly earlier time of laryngeal mask removal of(8.3±2.1)min than(18.2±1.8)min in group C;group M had significantly lower utilization rate of muscle relaxant antagonists than 62.5%in group C(P<0.05).In group M,5 cases had skin flushing,2 cases had choking when placing the laryngeal mask,and 3 cases had laryngeal mask leakage;in group C,2 cases had skin flushing,2 cases had choking when placing the laryngeal mask,and 2 cases had laryngeal mask leakage.There was no statistically significant difference in the incidence of perioperative adverse events between the two groups(P>0.05).Conclusion Mivacurium chloride used in children's strabismus corrective surgery hhas a short recovery time for muscle relaxation,a fast time for laryngeal mask removal,and less use of muscle relaxation antagonists.It has certain advantages in rapid surgical recovery.
Mivacurium chlorideCis-atracuriumStrabismus in childrenMuscle relaxant effect
万方数据
维普
