首页|丹参多酚酸盐联合甲钴胺治疗糖尿病周围神经病变的效果分析

丹参多酚酸盐联合甲钴胺治疗糖尿病周围神经病变的效果分析

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目的 分析丹参多酚酸盐与甲钴胺协同治疗糖尿病周围神经病变(DPN)的效果.方法 102 例DPN患者,按照随机数字表法分为对照组(51 例)与研究组(51 例).对照组应用甲钴胺治疗,研究组在甲钴胺治疗的基础上联合丹参多酚酸盐治疗.比较两组患者的疗效、多伦多临床评分系统(TCSS)评分以及不良反应发生率.结果 研究组的总有效率 96.08%高于对照组的 80.39%(P<0.05).治疗前,两组TCSS评分比较,结果无差异性(P>0.05);治疗 4 周后,研究组TCSS评分(7.05±2.20)分低于对照组的(8.57±1.75)分(P<0.05).两组不良反应发生率比较,结果无差异性(P>0.05).结论 丹参多酚酸盐与甲钴胺协同治疗DPN效果确切,可以有效改善患者的神经功能,适于临床应用.
Effect analysis of salvianolate combined with mecobalamin on diabetic peripheral neuropathy
Objective To analyze the effect of salvianolate combined with mecobalamin on diabetic peripheral neuropathy.Methods 102 DPN patients were divided into a control group(51 cases)and a study group(51 cases)according to the random number table.The control group was treated with mecobalamine,and the study group was treated with salvianolate combined with mecobalamine.The efficacy,Toronto Clinical Scoring System(TCSS)score and incidence of adverse reactions were compared between the two groups.Results The total effective rate of 96.08%in the study group was higher than 80.39%in the control group(P<0.05).Before treatment,there was no difference in TCSS scores between the two groups(P>0.05).After 4 weeks of treatment,TCSS score of(7.05±2.20)points in the study group was lower than(8.57±1.75)points in the control group(P<0.05).There was no difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion The synergistic treatment of DPN with salvianolate and mecobalamin is effective,can effectively improve the patient's neurological function.It has good safety,and is suitable for clinical application.

SalvianolateMecobalaminDiabetic peripheral neuropathy

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251600 商河县人民医院

丹参多酚酸盐 甲钴胺 糖尿病周围神经病变

2024

中国现代药物应用
中国水利电力医学科学技术学会

中国现代药物应用

影响因子:0.862
ISSN:1673-9523
年,卷(期):2024.18(10)