中国现代药物应用2024,Vol.18Issue(11) :14-17.DOI:10.14164/j.cnki.cn11-5581/r.2024.11.004

哌拉西林/他唑巴坦治疗泌尿系统感染的疗效分析

Efficacy analysis of piperacillin/tazobactam in the treatment of urinary system infection

洪建兴 施巧微
中国现代药物应用2024,Vol.18Issue(11) :14-17.DOI:10.14164/j.cnki.cn11-5581/r.2024.11.004

哌拉西林/他唑巴坦治疗泌尿系统感染的疗效分析

Efficacy analysis of piperacillin/tazobactam in the treatment of urinary system infection

洪建兴 1施巧微2
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作者信息

  • 1. 362200 晋江市医院晋南分院肾内科
  • 2. 362200 晋江市医院手术室
  • 折叠

摘要

目的 探讨泌尿系统感染应用哌拉西林/他唑巴坦治疗的效果.方法 75 例泌尿系统感染患者,依照治疗方案的不同分为对照组(28 例)和研究组(47 例).对照组采用左氧氟沙星治疗,研究组采用哌拉西林/他唑巴坦治疗.对比两组疗效、细菌清除率及不良反应发生率.结果 研究组总有效率 91.5%较对照组的 71.4%高(P<0.05).研究组菌株为 37 株,对照组为 21 株,研究组细菌清除率86.5%(32/37)与对照组的85.7%(18/21)对比无差异(P>0.05).研究组不良反应发生率4.3%与对照组的3.6%对比无差异(P>0.05).结论 在泌尿系统感染中,哌拉西林/他唑巴坦治疗效果好,且安全性较高,值得应用与推广.

Abstract

Objective To explore the effect of piperacillin/tazobactam in the treatment of urinary system infection.Methods 75 patients with urinary tract infection were divided into a control group(28 cases)and a study group(47 cases)according to different treatment plans.The control group was treated with levofloxacin,and the study group was treated with piperacillin/tazobactam.The clinical efficacy,bacterial clearance rate and adverse reactions of the two groups were compared.Results The total effective rate of the study group was 91.5%,which was higher than 71.4%of the control group(P<0.05).There were 37 strains in the study group and 21 strains in the control group.The bacterial clearance rate in the study group was 86.5%(32/37),which was not different from 85.7%(18/21)in the control group(P>0.05).There was no difference in the incidence of adverse reactions between the study group(4.3%)and the control group(3.6%)(P>0.05).Conclusion Piperacillin/tazobactam is effective and safe in the treatment of urinary system infection,which is worthy of application and promotion.

关键词

泌尿系统感染/哌拉西林/他唑巴坦/临床疗效/不良反应

Key words

Urinary system infection/Piperacillin/tazobactam/Clinical efficacy/Adverse reactions

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出版年

2024
中国现代药物应用
中国水利电力医学科学技术学会

中国现代药物应用

影响因子:0.862
ISSN:1673-9523
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