Application of intravenously administered dexmedetomidine in combined spinal-epidural anesthesia for cesarean section
Objective To analyze the application value of intravenously administered dexmedetomidine in combined spinal-epidural anesthesia for cesarean section,and provide reference for related research work.Methods A total of 72 women receiving combined spinal-epidural anesthesia for cesarean section were selected as the study samples,and the subjects were divided into the new group(36 cases)and the traditional group(36 cases)according to whether dexmedetomidine was used during the operation.Subjects in the traditional group did not apply sedative and analgesic drugs intraoperatively,and subjects in the new group applied dexmedetomidine intraoperatively.The heart rate and mean arterial pressure(MAP)at each stage[before anesthesia(T0),10 min after anesthetic injection(T1)and 30 min after anesthetic injection(T2)],analgesic effect and neonatal Apgar score of the two groups were compared.Results At T0,there were no significant differences in MAP and heart rate between the two groups(P>0.05).MAP and heart rate at T1 and T2 were significantly increased compared with those at T0 of the traditional group(P<0.05).MAP and heart rate of the new group at T1 and T2 showed fluctuations compared with those at T0,but there was no significant difference(P>0.05).Compared with the traditional group,MAP and heart rate were lower in the new group at T1 and T2(P<0.05).The total effective rate of anesthesia and analgesia in the new group was 100.00%,which was higher than 88.89%in the traditional group(P<0.05).The Apgar scores at 1,5 and 10 min after birth in the new group were(9.55±0.66),(9.77±0.18)and(9.98±0.03)points,while those in the traditional group were(8.36±0.72),(8.88±0.42)and(9.18±0.29)points.The Apgar scores at 1,5 and 10 min after birth in the new group were higher than those in the traditional group(P<0.05).Conclusion For women undergoing combined spinal-epidural anesthesia for cesarean section,the intraoperative application of dexmedetomidine can achieve satisfactory analgesic effects,and this medication regimen has little impact on the MAP and heart rate of the women.This method helps to improve the perioperative comfort of the women,and has no significant impact on the newborn,and it is safe and worthy of further promotion and application in obstetrics.
DexmedetomidineIntravenously administeredCombined spinal-epidural anesthesiaCesarean sectionApplication value
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