Analysis of status quo and risk factors of cognitive impairment 3 months after the onset of acute ischemic stroke in patients>60 years old
Objective To analyze the status quo and risk factors of cognitive impairment 3 months after the onset of acute ischemic stroke in patients>60 years old.Methods 168 patients>60 years old with acute ischemic stroke were studied,and their general data were collected to analyze the factors affecting cognitive impairment 3 months after the onset of acute ischemic stroke.Results 67(39.88%)of the 168 patients>60 years old had cognitive impairment 3 months after onset of acute ischemic stroke.The percentages of>70 years of age,hypertension,diabetes,National Institutes of Health Stroke Scale(NIHSS)score>15 points,Fazekas grading≥grade 2,malnutrition,arterial systolic pressure variability>10%,and comorbid obstructive sleep apnea of patients with cognitive impairment were higher than those of patients without cognitive impairment(P<0.05).Comparison of gender ratios between patients with cognitive impairment and those without cognitive impairment(P>0.05).Logistic regression analysis showed that>70 years of age,hypertension,diabetes,NIHSS score>15 points,Fazekas grading≥grade 2,arterial systolic pressure variability>10%,obstructive sleep apnea were independent risk factors for cognitive impairment 3 months after the onset of acute ischemic stroke in patients>60 years old(OR=1.967,1.483,1.511,2.369,2.158,1.795,1.214;P<0.05),and good nutritional status was independent protective factor for cognitive impairment 3 months after the onset of acute ischemic stroke in patients>60 years old(OR=0.682,P<0.05).Conclusion Age,hypertension,diabetes,NIHSS score,Fazekas grade,arterial systolic pressure variability,obstructive sleep apnea and nutritional status were all influential factors for cognitive impairment 3 months after the onset of acute ischemic stroke in patients>60 years old,and it is necessary to strengthen targeted intervention.
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NSTL
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