The therapeutic effect of tinidazole suppositories and Fuke Qianjin capsules on senile vaginitis
Objective To explore the therapeutic effect of tinidazole suppositories and Fuke Qianjin capsules on senile vaginitis.Methods 320 elderly patients with vaginitis were randomly divided into a non-Qianjin capsule group and a Qianjin capsule group,with 160 patients in each group.The non-Qianjin capsule group was treated with tinidazole suppositories,while the Qianjin capsule group was treated with tinidazole suppositories and Fuke Qianjin capsules.The symptom score,vaginal health index score,efficacy and adverse reactions were compared between the two groups.Results After treatment,the scores of external genital/vaginal itching,vaginal burning/pain,secretion characteristics,sexual intercourse pain,and abdominal distension pain in Qianjin capsule group were(1.11±0.33),(1.23±0.25),(1.35±0.27),(1.23±0.42)and(1.26±0.35)points,which were significantly lower than(1.86±0.26),(1.79±0.33),(1.86±0.25),(1.91±0.24)and(1.95±0.24)points in non-Qianjin capsule group(P<0.05).After treatment,the scores of vaginal mucosal morphology,wetness,vaginal fold elasticity,vaginal pH value,and vaginal cleanliness in Qianjin capsule group were(1.52±0.42),(1.46±0.33),(1.23±0.15),(1.45±0.22)and(1.52±0.42)points,which were significantly lower than(2.11±0.37),(1.82±0.35),(1.86±0.34),(1.91±0.23)and(1.89±0.18)points in non-Qianjin capsule group(P<0.05).The total effective rate of Qianjin capsule group(97.50%,156/160)was significantly higher than that of non-Qianjin capsule group(78.75%,126/160)(P<0.05).There was no significant difference in the incidence of adverse reactions between Qianjin capsule group(8.13%,13/160)and non-Qianjin capsule group(6.25%,10/160)(P>0.05).Conclusion The combination treatment of tinidazole suppositories and Fuke Qianjin capsules can effectively improve the vaginal health level and clinical symptoms of patients,and it is safely and reliable in the treatment of senile vaginitis.
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