摘要
目的 探究超早期气管插管治疗重型颅脑损伤患者的效果.方法 选择重型颅脑损伤患者 60 例,依据随机数字表法分为观察组(采用超早期气管插管治疗)及对照组(采用常规气管插管治疗),各 30 例.比较两组生命体征[平均动脉压(MAP)、心率(HR)、血氧饱和度(SpO2)]、生活能力评分、临床疗效、肺部感染发生率、呼吸功能指标[呼吸频率(RR)、动脉血二氧化碳分压(PaCO2)、动脉血氧分压(PaO2)].结果 观察组MAP、SpO2、HR分别为(88.65±7.96)mm Hg(1 mm Hg=0.133 kPa)、(97.29±1.78)%、(71.12±4.20)次/min,均高于对照组的(63.83±7.08)mm Hg、(92.02±1.84)%、(64.26±3.50)次/min,差异有统计学意义(P<0.05).治疗后,观察组Barthel指数(58.36±13.16)分高于对照组的(51.10±12.05)分,差异有统计学意义(P<0.05).观察组治疗总有效率 86.67%高于对照组的 60.00%,差异有统计学意义(P<0.05).观察组肺部感染发生率 3.33%低于对照组的 20.00%,差异有统计学意义(P<0.05).观察组PaO2(82.66±23.52)mm Hg高于对照组的(70.53±21.11)mm Hg,RR(18.45±2.16)次/min、PaCO2(35.41±10.20)mm Hg均低于对照组的(21.31±3.10)次/min、(42.75±13.29)mm Hg,差异有统计学意义(P<0.05).结论 针对重型颅脑损伤患者,积极实施超早期气管插管治疗,可改善患者生命体征,提升生活能力,降低肺部感染情况的出现,提升对重型颅脑损伤的治疗效果,改善呼吸功能指标,适合应用于临床推广.
Abstract
Objective To investigate the effect of ultra-early tracheal intubation on patients with severe craniocerebral injury.Methods 60 patients with severe craniocerebral injury were selected and divided into an observation group(receiving ultra-early tracheal intubation)and a control group(receiving conventional tracheal intubation)according to random number table method,each with 30 cases.Both groups were compared in terms of vital signs[mean arterial pressure(MAP),heart rate(HR),blood oxygen saturation(SpO2)],life ability score,clinical efficacy,incidence of pulmonary infection,respiratory function indicators[respiratory rate(RR),arterial partial pressure of carbon dioxide(PaCO2),arterial partial pressure of oxygen(PaO2)].Results In the observation group,MAP,SpO2 and HR were(88.65±7.96)mm Hg(1 mm Hg=0.133 kPa),(97.29±1.78)%and(71.12±4.20)beats/min,which were higher than(63.83±7.08)mm Hg,(92.02±1.84)%and(64.26±3.50)beats/min in the control group,and the difference was statistically significant(P<0.05).After treatment,the observation group had higher Barthel index of(58.36±13.16)points than(51.10±12.05)points in the control group,and the difference was statistically significant(P<0.05).The total effective rate of the observation group was 86.67%,which was higher than 60.00%of the control group,and the difference was statistically significant(P<0.05).The incidence of pulmonary infection in the observation group was 3.33%,which was lower than 20.00%in the control group,and the difference was statistically significant(P<0.05).The observation group had higher PaO2 of(82.66±23.52)mm Hg than(70.53±21.11)mm Hg in the control group;the observation group had RR of(18.45±2.16)times/min and PaCO2 of(35.41±10.20)mm Hg,which were lower than(21.31±3.10)times/min and(42.75±13.29)mm Hg in the control group;the difference was statistically significant(P<0.05).Conclusion For patients with severe craniocerebral injury,active implementation of ultra-early tracheal intubation can improve patients'vital signs,enhance living ability,reduce the occurrence of pulmonary infection,improve the therapeutic effect of severe craniocerebral injury,and improve respiratory function indicators,which is suitable for clinical promotion.