Clinical effect of Miacalcic combined with Kirschner's wire fixation in the treatment of osteoporotic distal radius fracture and its influence on healing time
Objective To analyze the clinical efficacy of Salmon calcitonin injection(trade name:Miacalcic)combined with Kirschner's wire fixation in the treatment of osteoporotic distal radius fracture and its influence on healing time.Methods A total of 80 patients with osteopolitic distal radius fracture were divided into a control group and an observation group by random number drawing method,with 40 cases in each group.The control group was treated with Kirschner's wire fixation,and the observation group was combined with Miacalcic on this basis.Barthel index and visual analogue scale(VAS)score before and after treatment,clinical efficacy,and joint recovery were compared between two groups.Methods Before treatment,there was no significant difference in Barthel index and VAS score between the two groups(P>0.05).After treatment,the observation group had higher Barthel index of(83.27±7.37)points than(72.74±6.16)points in the control group,and the difference was statistically significant(P<0.05).VAS scores of the observation group at 1 week and 3 months after treatment were(2.49±0.31)and(1.02±0.23)points,which were lower than(3.36±0.42)and(2.38±0.35)points of the control group,and the difference was statistically significant(P<0.05).After treatment,the total effective rate of the observation group was 95.00%,which higher than that of the control group(77.50%),and the difference was statistically significant(χ2=5.165,P<0.05).After treatment,the observation group had higher bone mineral density of(0.72±0.26)g/cm2 than(0.61±0.22)g/cm2 in the control group;the observation group had fracture healing time of(30.31±4.72)d and the distance between the distal styloid of the radius and ulna of(0.68±0.18)cm,which were shorter than(44.39±5.63)d and(1.16±0.24)cm in the control group;the difference was statistically significant(P<0.05).Before treatment,there was no significant difference in bone mineral density between groups(P>0.05).Conclusion In the treatment of osteoporotic distal radius fracture,the combination of Miacalcic and Kirschner's wire fixation can reduce pain,shorten bone healing time and promote body recovery.