Clinical value of MRD detection for Mycoplasma pneumoniae infection in children
Objective To observe the effectiveness and feasibility of microbial rapid detection(MRD)in diagnosing Mycoplasma pneumoniae infection in children.Methods 85 children with suspected Mycoplasma pneumoniae infection were tested by enzyme-linked immunosorbent assay(ELISA)and MRD.The results of pathological examination were used as the gold standard to compare the diagnostic efficacy of the two methods for mycoplasma pneumoniae infection in children,and the satisfaction of parents with the two methods.Results Pathological results:of 85 children with suspected Mycoplasma pneumoniae infection,75 cases were positive and 10 cases were negative.ELISA test results:66 cases were positive and 19 cases were negative;MRD test results:70 cases were positive and 15 cases were negative.The specificity of MRD for the diagnosis of Mycoplasma pneumoniae infection in children was 80.00%,the sensitivity was 90.67%,the accuracy was 89.41%,the positive predictive value was 97.14%,and the negative predictive value was 53.33%,which were higher than 20.00%,77.33%,70.59%,87.88%and 10.53%of ELISA(P<0.05).The overall satisfaction rate of parents with MRD was 95.29%,which was significantly higher than 85.88%of ELISA(P<0.05).Conclusion MRD detection has high diagnostic efficacy for Mycoplasma pneumoniae infection in children,and is worthy of further clinical application.
Mycoplasma pneumoniae infection in childrenEnzyme linked immunosorbent assayMicrobial rapid detection
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