Clinical value analysis of butylohthalide soft capsules combined with edaravone in the treatment of cerebral infarction
Objective To analyze the clinical value of butylohthalide soft capsules combined with edaravone in the treatment of cerebral infarction.Methods 84 patients with cerebral infarction were randomly divided into a control group and a study group,with 42 cases in each group.The control group was treated with edaravone,and the study group was treated with butylohthalide soft capsules on the basis of the control group.The therapeutic effect,neurological impairment,exercise ability,hemorheology index and quality of life of the two groups were compared.Results The total effective rate of the study group was 97.62%,which was higher than the control group's 85.71%(χ2=3.896,P=0.048<0.05).After treatment,the National Institutes of Health Stroke Scale(NIHSS)score in both groups was decreased,and the score of the study group[(10.04±1.12)points]was lower than that of the control group[(16.98±1.34)points].The difference was statistically significant(P<0.05).After treatment,the Fugel-Meyer score of both groups was improved,among which,the score of the study group[(76.45±3.54)points]was higher than that of the control group[(66.28±3.71)points].The difference was statistically significant(P<0.05).After treatment,the plasma viscosity,hematocrit and whole blood high shear viscosity were decreased in both groups;the plasma viscosity,hematocrit and whole blood high shear viscosity in the study group were(1.18±0.16)mPa·s,(40.01±2.01)%and(4.03±0.32)mPa·s,which were lower than(2.68±0.20)mPa·s,(43.67±2.02)%and(5.52±0.33)mPa·s in the control group;the difference was statistically significant(P<0.05).After treatment,the 36-item short-form health survey(SF-36)scores of both groups were improved,among which,the score of the study group[(91.46±3.74)points]was higher than that of the control group[(85.14±2.85)points].The difference was statistically significant(P<0.05).Conclusion The combination of butylohthalide soft capsules and edaravone in the treatment of cerebral infarction has a good clinical effect,and it has a good promoting effect on the improvement of brain tissue function and the optimization of prognosis and health of patients.Therefore,medical personnel should actively pay close attention to this therapy.
Cerebral infarctionButylohthalide soft capsulesEdaravoneClinical effectQuality of life
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