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孕期补充叶酸及微量元素对孕妇妊娠结局的影响

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目的 探讨孕期补充叶酸及微量元素对孕妇妊娠结局的影响.方法 以 254 例分娩孕妇作为研究对象,根据孕妇补充叶酸和微量元素情况进行分组,其中 132 例孕妇在妊娠前和妊娠早期补充叶酸和微量元素作为研究组,妊娠前补充时间超过 1 个月,妊娠早期补充时间 3 个月;122 例孕妇仅在妊娠早期单一补充叶酸作为对照组,补充时间 3 个月.比较两组孕妇的分娩方式、妊娠期并发症发生率及新生儿营养状况.结果 研究组孕妇妊娠期并发症发生率为 6.06%,明显低于对照组的 15.57%,差异具有统计学意义(P<0.05);研究组孕妇的顺产率 63.64%明显高于对照组的 48.36%,剖宫产率 12.12%明显低于对照组的 30.33%,差异具有统计学意义(P<0.05);助产率组间比较差异无统计学意义(P>0.05);两组新生儿的身高、头围以及胸围比较,差异无统计学意义(P>0.05).结论 妊娠期间规范化补充微量元素和叶酸可以有效减少孕妇妊娠期并发症的发生率,提高顺产率,降低剖宫产率.
Effects of folic acid and trace elements supplementation during pregnancy on pregnancy outcomes
Objective To explore the effects of folic acid and trace elements supplementation during pregnancy on pregnancy outcomes.Methods A total of 254 pregnant women who gave birth were divided into groups according to folic acid and trace elements supplementation.132 pregnant women supplemented folic acid and trace elements before pregnancy and in early pregnancy were selected as the study group,with the supplementation time of more than 1 month in pre-pregnancy and 3 months in early pregnancy,and 122 cases of pregnant women supplemented with a single folic acid in early pregnancy as the control group,with the supplementation time of 3 months.The mode of delivery,incidence of pregnancy complications and neonatal nutrition were compared between the two groups.Results The incidence of pregnancy complications in the study group was 6.06%,which was significantly lower than 15.57%in the control group,and the difference was statistically significant(P<0.05).The study group had significantly higher vaginal delivery rate of 63.64%than 48.36%in the control group,and significantly lower cesarean section rate of 12.12%than 30.33%in the control group.The difference was statistically significant(P<0.05).There was no significant difference in midwifery rate between the two groups(P>0.05).There was no significant difference in neonatal height,head circumference and chest circumference between the two groups(P>0.05).Conclusion The standardized supplementation of trace elements and folic acid during pregnancy can effectively reduce the incidence of pregnancy complications,improve the vaginal delivery rate and reduce the cesarean section rate.

PregnancyFolic acidTrace elementsPregnancy outcomeMode of delivery

李艳芳、郝长付

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450001 郑州大学公共卫生学院儿少卫生与妇幼保健系

孕期 叶酸 微量元素 妊娠结局 分娩方式

2024

中国现代药物应用
中国水利电力医学科学技术学会

中国现代药物应用

影响因子:0.862
ISSN:1673-9523
年,卷(期):2024.18(12)