Clinical study on the treatment of convalescent cerebral infarction with Qi deficiency and blood stasis syndrome by combination of traditional Chinese and Western medicine
Objective To explore the clinical effect of combination of traditional Chinese and Western medicine in the treatment of convalescent cerebral infarction with Qi deficiency and blood stasis syndrome.Methods 600 cases of convalescent cerebral infarction with Qi deficiency and blood stasis syndrome were divided into a control group and an observation group by simplified random method,with 300 cases in each group.The control group was treated with oral aspirin enteric-coated tablets,and the observation group was treated with Buyang Huanwu decoction based on the control group.The clinical efficacy,traditional Chinese medicine syndrome score,National Institutes of Health Stroke Scale(NIHSS)score,plasma fibrinogen(FIB)level,maximum platelet aggregation rate(MAR)and the occurrence of adverse reactions were observed and compared between the two groups.Results After treatment,the total clinical effective rate of the observation group(97.3%)was significantly higher than that of the control group(88.3%)(P<0.05).Compared with before treatment,the traditional Chinese medicine syndrome score of both groups improved after treatment(P<0.05).The traditional Chinese medicine syndrome score of(0.79±0.15)points in the observation group was significantly lower than(1.67±0.41)points in the control group(P<0.05).Compared with before treatment,the NIHSS scores in both groups decreased at 3,7 and 14 d after treatment(P<0.05).At 3,7 and 14 d after treatment,the NIHSS scores of the observation group were(10.08±2.69),(6.83±2.31)and(4.81±1.46)points,which were significantly lower than(11.32±2.58),(9.64±2.25)and(7.23±2.05)points of the control group(P<0.05).Compared with before treatment,the levels of FIB and MAR in both groups decreased after treatment(P<0.05).Compared with(3.67±0.82)g/L and(63.55±6.05)%in the control group,FIB of(2.85±0.49)g/L and MAR of(51.39±5.16)%in the observation group reduced significantly after treatment(P<0.05).The incidence of adverse reactions was 2.7%in the control group and 2.0%in the observation group.There was no statistical significance in the incidence of adverse reactions between the two groups(P>0.05).Conclusion The combination of traditional Chinese and Western medicine has significant clinical effect in patients with convalescent cerebral infarction with Qi deficiency and blood stasis syndrome,which can effectively alleviate the clinical symptoms and neurological impairment of patients,reduce thrombosis,and has high safety,which is worthy of clinical promotion and use.