The application value of bronchoscopic alveolar lavage combined with high-frequency chest wall oscillation in the treatment of lobar pneumonia
Objective To explore the clinical effect and application value of bronchoscopic alveolar lavage combined with high-frequency chest wall oscillation devices in the treatment of children with lobar pneumonia.Methods 60 children with lobar pneumonia were divided into a control group(30 cases)and an observation group(30 cases)by simple randomization method.The control group received conventional symptomatic treatment combined with high-frequency chest wall oscillation devices,and the observation group received bronchoscopic alveolar lavage on the basis of the control group.Patients in both groups were compared in terms of clinical efficacy,pulmonary function indexes(maximum mid-expiratory flow,forced expiratory volume in one second and forced vital capacity),serum inflammatory markers[procalcitonin(PCT),C-reactive protein(CRP)]and incidence of adverse events.Results Compared with the control group(80.0%),the total clinical effective rate of the observation group(96.7%)was significantly increased(P<0.05).Compared with before treatment,the maximum mid-expiratory flow,forced expiratory volume in one second and forced vital capacity in both groups were increased after treatment(P<0.05).After treatment,the maximum mid-expiratory flow in the observation group was(1.92±0.38)L/s,the forced expiratory volume in one second was(1.85±0.33)L,and the forced vital capacity was(3.54±0.67)L,which were higher than(1.32±0.31)L/s,(1.27±0.29)L,and(2.15±0.48)L in the control group(P<0.05).Compared with before treatment,the serum CRP and PCT levels in both groups were decreased after treatment(P<0.05).After treatment,the observation group had serum CRP of(2.27±0.19)mg/L and PCT of(0.08±0.02)ng/ml,which were significantly lower than(6.68±0.85)mg/L and(0.16±0.05)ng/ml in the control group(P<0.05).There was no significant difference in the incidence of adverse events between the two groups(P>0.05).Conclusion Bronchoscopic alveolar lavage combined with high-frequency oscillatory expectoration has significant clinical efficacy in children with lobar pneumonia,which can effectively improve lung function and reduce the level of inflammatory factors of children.It is safe and worthy of clinical promotion and application.
Lobar pneumoniaBronchoscopic alveolar lavageHigh-frequency chest wall oscillation devicesPulmonary function
NETL
NSTL
万方数据
