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半夏厚朴汤治疗分泌性中耳炎的效果观察

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目的 对分泌性中耳炎患者治疗中使用半夏厚朴汤的临床效果进行分析研究。方法 抽取 78 例分泌性中耳炎患者,随机划分为研究组与对照组,各 39 例。对照组患者给予常规西药治疗,研究组患者予以半夏厚朴汤治疗。对比两组患者中医证候积分、治疗效果、不良反应发生情况、炎症因子[降钙素原(PCT)、C反应蛋白(CRP)、肿瘤坏死因子-α(TNF-α)]水平。结果 研究组患者耳痛、耳鸣、耳闷、中耳积液、听力下降积分分别为(0。50±0。24)、(0。42±0。16)、(0。75±0。23)、(0。56±0。14)、(0。57±0。16)分,显著低于对照组的(1。56±0。43)、(1。62±0。48)、(1。72±0。35)、(1。40±0。26)、(1。47±0。25)分,对比存在统计学价值(P<0。05)。研究组治疗总有效率 97。44%显著高于对照组的 82。05%,对比存在统计学价值(P<0。05)。研究组的不良反应发生率 2。56%显著低于对照组的 15。38%,对比存在统计学价值(P<0。05)。治疗后,研究组患者PCT(0。18±0。05)ng/ml、CRP(3。55±0。33)mg/L、TNF-α(30。51±8。03)pg/ml显著低于对照组的(0。36±0。09)ng/ml、(5。03±0。35)mg/L、(45。62±9。34)pg/ml,对比存在统计学价值(P<0。05)。结论 在分泌性中耳炎治疗中,半夏厚朴汤能够改善患者临床症状,有利于降低其炎性因子水平,从而提高治疗效果。
Observation on the effect of Banxia Houpu Decoction on secretory otitis media
Objective To study the clinical effect of Banxia Houpu Decoction on secretory otitis media.Methods 78 patients with secretory otitis media were randomly divided into a study group and a control group,each with 39 cases.The control group was treated with conventional western medicine,and the study group was treated with Banxia Houpu Decoction.The traditional Chinese medicine syndrome score,treatment effect,occurrence of adverse reactions,and levels of inflammatory factors[procalcitonin(PCT),C-reactive protein(CRP),tumor necrosis factor-α(TNF-α)]were compared between the two groups.Results The scores of ear pain,tinnitus,aural fullness,middle ear effusion and hearing loss were(0.50±0.24),(0.42±0.16),(0.75±0.23),(0.56±0.14)and(0.57±0.16)points in the study group,which were significantly lower than(1.56±0.43),(1.62±0.48),(1.72±0.35),(1.40±0.26)and(1.47±0.25)points in the control group,and there was statistical value(P<0.05).The total effective rate of the study group was 97.44%,which was significantly higher than 82.05%of the control group,and there was statistical value(P<0.05).The incidence of adverse reactions in the study group was 2.56%,which was significantly lower than 15.38%in the control group,and there was statistical value(P<0.05).After treatment,the study group had PCT of(0.18±0.05)ng/ml,CRP of(3.55±0.33)mg/L,TNF-α of(30.51±8.03)pg/ml,which were significantly lower than(0.36±0.09)ng/ml,(5.03±0.35)mg/L,(45.62±9.34)pg/ml in the control group,and there was statistical value(P<0.05).Conclusion In the treatment of secretory otitis media,Banxia Houpu Decoction can improve the clinical symptoms of patients,and help to reduce the level of inflammatory factors,so as to improve the therapeutic effect.

Secretory otitis mediaBanxia Houpu DecoctionInflammatory factorsTraditional Chinese medicine syndrome scoreAdverse reaction

孙学芬

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252000 聊城市眼科医院

分泌性中耳炎 半夏厚朴汤 炎性因子 中医证候积分 不良反应

2024

中国现代药物应用
中国水利电力医学科学技术学会

中国现代药物应用

影响因子:0.862
ISSN:1673-9523
年,卷(期):2024.18(13)
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