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喉咽清颗粒治疗儿童急性扁桃体炎的临床效果研究

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目的 探讨喉咽清颗粒治疗儿童急性扁桃体炎的临床效果。方法 106 例儿童急性扁桃体炎患儿,以随机方式分为对照组和研究组,各 53 例。对照组选择常规西药治疗,研究组在对照组的基础上联合喉咽清颗粒进行治疗。比较两组患儿治疗效果、炎性因子[白细胞介素-6(IL-6)、降钙素原(PCT)、C反应蛋白(CRP)]水平、免疫指标[免疫球蛋白(Ig)G、IgA、IgM]水平、不良反应发生情况。结果 研究组治疗总有效率 94。3%比对照组的 75。5%更高(P<0。05)。研究组患儿IL-6(28。5±6。6)pg/ml、PCT(0。2±0。1)ng/ml、CRP(9。3±2。4)mg/L均低于对照组的(34。5±8。2)pg/ml、(0。8±0。1)ng/ml、(13。6±3。2)mg/L,IgG(9。5±2。6)g/L、IgA(1。5±0。7)mg/L、IgM(1。9±0。6)g/L均高于对照组的(8。1±2。3)g/L、(1。2±0。8)mg/L、(1。5±0。6)g/L(P<0。05)。研究组恶心、呕吐、腹泻、皮疹发生率分别为 0、0、1。9%、1。9%,均低于对照组的 9。4%、7。5%、13。2%、13。2%(P<0。05)。结论 喉咽清颗粒联合常规西药治疗儿童急性扁桃体炎的效果明显,能够有效改善患儿的具体临床病症,并消除炎性反应,提高免疫功能,降低不良反应发生率,可以推广应用。
Study on clinical effect of Houyanqing granules in the treatment of acute tonsillitis in children
Objective To explore the clinical effect of Houyanqing granules in the treatment of acute tonsillitis in children.Methods 106 children with acute tonsillitis were randomly divided into a control group and a study group,with 53 cases in each group.The control group was treated with conventional western medicine,and the study group was treated with Houyanqing granules.The therapeutic effect,inflammatory factors[interleukin-6(IL-6),procalcitonin(PCT),C-reactive protein(CRP)]levels,immune indexes[immunoglobulin(Ig)G,IgA,IgM]levels and the occurrence of adverse reactions were compared between the two groups.Results The total effective rate of the study group was 94.3%,which was higher than 75.5%of the control group(P<0.05).The study group had IL-6 of(28.5±6.6)pg/ml,PCT of(0.2±0.1)ng/ml and CRP of(9.3±2.4)mg/L,which were lower than(34.5±8.2)pg/ml,(0.8±0.1)ng/ml and(13.6±3.2)mg/L in the control group;the study group had IgG of(9.5±2.6)g/L,IgA of(1.5±0.7)mg/L and IgM of(1.9±0.6)g/L,which were higher than(8.1±2.3)g/L,(1.2±0.8)mg/L and(1.5±0.6)g/L in the control group(P<0.05).The incidence of nausea,vomiting,diarrhea and rash in the study group were 0,0,1.9%and 1.9%,which were lower than 9.4%,7.5%,13.2%and 13.2%in the control group(P<0.05).Conclusion Houyanqing granules combined with conventional western medicine has obvious effect in the treatment of acute tonsillitis in children,which can effectively improve the specific clinical symptoms of children,eliminate inflammatory reaction,improve the immune function,and reduce the overall incidence of adverse reactions.It can be widely used.

Houyanqing granulesAcute tonsillitis in childrenInflammatory factorsClinical effectSecurity

李春花、詹雅兰、谷艳龙

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410205 湖南航天医院儿科

喉咽清颗粒 儿童急性扁桃体炎 炎性因子 临床效果 安全性

2024

中国现代药物应用
中国水利电力医学科学技术学会

中国现代药物应用

影响因子:0.862
ISSN:1673-9523
年,卷(期):2024.18(13)
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