Analysis of clinical efficacy of ultrasound-guided radiofrequency ablation on adenomyosis
Objective To explore the clinical efficacy of ultrasound-guided radiofrequency ablation on adenomyosis.Methods 40 patients with adenomyosis were divided into a control group and an observation group by random number table method,with 20 cases in each group.The control group received conservative drug treatment,and the observation group received ultrasound-guided radiofrequency ablation on the basis of conservative drug treatment.The clinical efficacy,lesion and uterine volume,endometrial thickness,dysmenorrhea,menstrual volume and anemia,risk of recurrence[carbohydrate antigen(CA)125 and vascular endothelial growth factor(VEGF)levels]were compared between the two groups.Results The total effective rate of the observation group was 95.00%,which was higher than 65.00%of the control group(P<0.05).After 3 months of treatment,the uterine volume and lesion volume in both groups were smaller than those before treatment,and the endometrial thickness was lower than that before treatment;the uterine volume of(92.57±14.28)cm3 and lesion volume of(42.36±10.55)cm3 in the observation group were smaller than(132.48±16.31)and(64.47±12.31)cm3 in the control group;the endometrial thickness of(5.72±0.74)mm in the observation group was lower than(6.84±0.95)mm in the control group(P<0.05).After 3 months of treatment,the pain score and pictorial blood loss assessment chart score of the two groups were lower than those before treatment,and the hemoglobin level was higher than that before treatment;the pain score of the observation group was(2.62±0.74)points,and the pictorial blood loss assessment chart score was(69.51±10.26)points,which were lower than(3.28±0.95)and(85.77±14.41)points of the control group;the hemoglobin level of(115.37±13.15)g/L of the observation group was higher than(104.46±12.87)g/L of the control group(P<0.05).After 3 months of treatment,the levels of CA125 and VEGF in both groups were lower than those before treatment;the observation group had CA125 of(30.45±17.53)IU/ml and VEGF of(117.25±12.83)ng/L,which were lower than(72.31±21.04)IU/ml and(139.61±15.25)ng/L in the control group(P<0.05).Conclusion Ultrasound-guided radiofrequency ablation is effective in treating adenomyosis,which can improve dysmenorrhea,menstrual disorder and anemia and reduce the risk of recurrence.
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