摘要
目的 探究肥胖合并阻塞性睡眠呼吸暂停患者中应用多导睡眠图(PSG)监测对早期识别肥胖低通气综合征的价值.方法 选择 80 例肥胖合并阻塞性睡眠呼吸暂停患者,根据有无合并肥胖低通气综合征分为对照组(未合并肥胖低通气综合征)与观察组(合并肥胖低通气综合征),每组40 例.两组患者均于睡眠监测室接受整夜的PSG监测.对比两组PSG监测结果[呼吸紊乱指数(AHI)、最低动脉血氧饱和度(SaO2)、最长呼吸暂停时间、收缩压、快速眼动期(REM)占比及非快速眼动期(NREM)Ⅲ和Ⅳ期占比].结果 观察组AHI(15.36±6.35)次/h、最低SaO2(53.15±15.36)%、最长呼吸暂停时间(11.25±3.41)s、收缩压(115.84±10.65)mm Hg(1 mm Hg=0.133 kPa)、REM占比(26.45±2.41)%以及NREMⅢ和Ⅳ期占比(11.65±3.65)%与对照组的(11.35±5.26)次/h、(72.14±19.32)%、(7.28±2.35)s、(94.35±7.12)mm Hg、(23.45±2.54)%、(14.55±3.45)%比较差异明显(P<0.05).结论 PSG在肥胖合并阻塞性睡眠呼吸暂停患者中早期识别肥胖低通气综合征具有一定的应用价值,通过PSG可以评估患者的呼吸事件、SaO2 和通气功能等参数,能帮助早期发现和干预肥胖低通气综合征,改善患者的睡眠质量和生活质量.
Abstract
Objective To explore the value of applying polysomnography(PSG)in early identification of obesity hypoventilation syndrome in obese patients with obstructive sleep apnea.Methods 80 obese patients with obstructive sleep apnea were selected.The patients were divided into a control group(without obesity hypoventilation syndrome)and an observation group(with obesity hypoventilation syndrome)based on the presence or absence of obesity hypoventilation syndrome,with 40 cases in each group.Patients in both groups underwent overnight PSG monitoring in the sleep monitoring room.The results of PSG monitoring[apnea hypopnea index(AHI),lowest arterial oxygen saturation(SaO2),longest apnea time,systolic blood pressure,sleep rapid eye movement(REM)ratio and ratio of stage Ⅲ/Ⅳ non-rapid eye movement(NREM)]were compared between the two groups.Results In the observation group,AHI was(15.36±6.35)times/h,the lowest SaO2 was(53.15±15.36)%,the longest apnea time was(11.25±3.41)s,the systolic blood pressure was(115.84±10.65)mm Hg(1 mm Hg=0.133 kPa),the REM ratio was(26.45±2.41)%and the stage Ⅲ/Ⅳ NREM ratio was(11.65±3.65)%,which were significantly different from(11.35±5.26)times/h,(72.14±19.32)%,(7.28±2.35)s,(94.35±7.12)mm Hg,(23.45±2.54)%,and(14.55±3.45)%in the control group(P<0.05).Conclusion PSG has certain application value in early identification of obesity hypoventilation syndrome in obese patients with obstructive sleep apnea.PSG can evaluate parameters such as respiratory events,SaO2,and ventilation function in patients,helping to detect and intervene in obesity hypoventilation syndrome early,and improving the sleep quality and quality of life of patients.
基金项目
2022年佛山市自筹经费类科技创新项目(2220001004664)
NETL
NSTL
万方数据