维生素D对孕妇和胎儿并发症的影响
Effects of vitamin D on maternal and fetal complications
张莹1
作者信息
- 1. 211300 南京市高淳区妇幼保健院孕产保健科
- 折叠
摘要
目的 分析维生素D对孕妇和胎儿并发症的影响.方法 纳入 300 例孕妇进行研究,均存在维生素D缺乏情况,按照随机分配方式分为对照组(150 例,给予常规管理)与实验组(150 例,在常规管理的基础上补充维生素D).对比两组低钙血症、骨质疏松、胎儿发育迟缓发生率及血清钙、骨密度水平,分析维生素D水平与孕妇和胎儿并发症发生率的相关性.结果 实验组低钙血症、骨质疏松、胎儿发育迟缓发生率分别为 4.67%、6.00%、6.67%,均低于对照组的 12.67%、18.00%、20.67%,数据差异显著,有统计学意义(P<0.05).实验组血清钙、骨密度水平分别为(2.62±1.21)mmol/L、(2.43±1.13)g/cm2,均高于对照组的(1.08±0.88)mmol/L、(1.02±1.48)g/cm2,数据差异显著,有统计学意义(P<0.05).Pearson相关分析显示,维生素D水平与孕妇和胎儿并发症发生率呈负相关(r=-0.548,P<0.05).结论 维生素D缺乏会增加孕妇低钙血症、骨质疏松及胎儿发育迟缓等并发症发生率,孕妇需要定期接受产检,了解自身维生素D、血清钙、骨密度水平等,合理补充维生素D,为孕妇与胎儿生命健康提供一定保障.
Abstract
Objective To analyze the effects of vitamin D on maternal and fetal complications.Methods 300 pregnant women were included for study,all with vitamin D deficiency,and were divided into a control group(150 cases,given routine management)and an experimental group(150 cases,given vitamin D supplementation on the basis of routine management)according to random allocation.The incidence of hypocalcemia,osteoporosis,fetal growth retardation,serum calcium and bone mineral density levels were compared between the two groups,and the correlation between vitamin D levels and the incidence of maternal and fetal complications was analyzed.Results The incidence rates of hypocalcemia,osteoporosis and fetal growth retardation in the experimental group were 4.67%,6.00%and 6.67%,which were lower than 12.67%,18.00%and 20.67%in the control group,with significant difference(P<0.05).The levels of serum calcium and bone mineral density in the experimental group were(2.62±1.21)mmol/L and(2.43±1.13)g/cm2,which were higher than(1.08±0.88)mmol/L and(1.02±1.48)g/cm2 in the control group,with significant differences(P<0.05).Pearson correlation analysis showed that vitamin D levels were negatively correlated with the incidence of maternal and fetal complications(r=-0.548,P<0.05).Conclusion Vitamin D deficiency will increase the incidence of complications such as hypocalcemia,osteoporosis and fetal growth retardation in pregnant women.Pregnant women need to receive regular prenatal examinations to understand their vitamin D,serum calcium and bone mineral density levels,and reasonably supplement vitamin D to provide certain protection for the life and health of pregnant women and fetuses.
关键词
维生素D/孕妇/胎儿/并发症Key words
Vitamin D/Pregnant woman/Fetus/Complications引用本文复制引用
出版年
2024
NETL
NSTL
万方数据