Analysis of the clinical effect of Huanglian Wendan Decoction combined with Banxia Baizhu Tianma Decoction in treating hypertensive vertigo
Objective To analyze the effect of Huanglian Wendan Decoction combined with Banxia Baizhu Tianma Decoction in treating hypertensive vertigo.Methods 50 patients with hypertensive vertigo were randomly divided into a conventional group and a study group by computer drawing method,with 25 cases in each group.The conventional group was treated with conventional western medicine,and the study group was treated with Huanglian Wendan Decoction combined with Banxia Baizhu Tianma Decoction.Patients in both groups were compared in terms of blood pressure[systolic blood pressure(SBP),diastolic blood pressure(DBP)],incidence of adverse reactions,vascular endothelial function index[calcitonin gene-related peptide(CGRP),endothelin-1(ET-1),thrombomodulin(TM)],traditional Chinese medicine vertigo rating score and dizziness handicap inventory(DHI)score.Results After treatment,the study group had SBP of(130.15±3.26)mm Hg(1 mm Hg=0.133 kPa)and DBP of(82.34±3.21)mm Hg,which were lower than(140.29±3.38)and(98.79±3.92)mm Hg in the conventional group.The difference was statistically significant(P<0.05).After treatment,the traditional Chinese medicine vertigo rating score and DHI score in the study group were(5.52±1.19)and(8.13±1.02)points,which were lower than(7.14±2.33)and(14.44±3.05)points in the conventional group.The difference was statistically significant(P<0.05).The incidence of adverse reactions of 4.00%in the study group was lower than 24.00%in the conventional group,and the difference was statistically significant(P<0.05).After treatment,CGRP of(39.48±4.07)ng/L in the study group was higher than(32.01±3.21)ng/L in the conventional group;the study group had ET-1 of(74.09±6.02)ng/L and TM of(1.15±0.11)μg/L,which were lower than(89.18±9.05)ng/L and(1.62±0.19)μg/L in the conventional group;the difference was statistically significant(P<0.05).Conclusion For patients with hypertensive vertigo,Huanglian Wendan Decoction combined with Banxia Baizhu Tianma Decoction can effectively alleviate clinical symptoms,regulate blood pressure,improve vascular endothelial function and reduce the occurrence of adverse reactions,which is of great clinical significance.
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