Observation on the effect of tirofiban hydrochloride combined with cardiovascular interventional surgery in the treatment of acute myocardial infarction
Objective To study the clinical effect of tirofiban hydrochloride combined with cardiovascular interventional surgery in the treatment of acute myocardial infarction.Methods 50 patients with acute myocardial infarction were selected,and were divided into an experimental group and a reference group by random number table method,each with 25 cases.The reference group was treated with cardiovascular interventional surgery,and the experimental group was treated with tirofiban hydrochloride combined with cardiovascular interventional surgery.The clinical efficacy,cardiac function indexes,TIMI blood flow grading and adverse events were compared between the two groups.Results The total effective rates of the experimental group and the reference group were 100.00% and 76.00%;the experimental group was higher than the reference group,and there was statistically significant difference(P<0.05).Before treatment,the left ventricular ejection fraction(LVEF)and left ventricular end diastolic diameter(LVEDD)of the experimental group were(50.93±5.31)% and(64.21±4.33)mm,respectively,while those of the control group were(50.89±5.27)% and(64.17±4.64)mm,respectively.After treatment,the LVEF and LVEDD of the experimental group were(58.04±4.56)% and(51.83±3.52)mm,respectively,while those of the control group were(52.94±4.73)% and(57.11±3.73)mm,respectively.Compared with before treatment,LVEF in the experimental group was significantly higher and higher than the reference group after treatment,and LVEDD was significantly lower and lower than the reference group.There was statistically significant difference(P<0.05).Compared with before treatment,LVEDD in the reference group was significantly lower after treatment,and there was statistically significant difference(P<0.05).The TIMI blood flow grading of the experimental group was better than that of the reference group,and there was statistically significant difference(P<0.05).After treatment,the incidence rate of adverse events in the experimental group was 4.00%,which was significantly lower than 32.00% in the reference group,and there was statistically significant difference(P<0.05).Conclusion Tirofiban hydrochloride combined with cardiovascular interventional surgery in the treatment of acute myocardial infarction has a good clinical effect,which can effectively improve the cardiac function and coronary artery flow status of patients,and reduce the occurrence of adverse events.
万方数据
维普
