Study on the value of serum procalcitonin in patients with respiratory infection
Objective To analyze the value of value of serum procalcitonin in patients with respiratory infection.Methods 50 patients with respiratory infections were taken as the infection group,and another 50 healthy subjects were taken as the reference group;Both groups received blood tests.The patients in the infected group were divided into a mild group and a severe group according to the severity of the disease,with 25 cases in each group;both groups were subjected to anti-infective treatment according to the requirements,and the blood tests were performed again after the treatment.Comparison of procalcitonin,C-reactive protein and white blood cell count between the infection group and the reference group,as well as between the mild group and severe group;comparison of the positive detection rate of respiratory infections by procalcitonin,C-reactive protein and white blood cell count;comparison of procalcitonin,C-reactive protein and white blood cell count before and after treatment in the infection group;comparison of procalcitonin,C-reactive protein and white blood cell count before and after treatment between the mild group and the severe group.Results In the infection group,the procalcitonin was(20.23±5.03)ng/ml,the C-reactive protein was(60.90±21.04)mg/L and the white blood cell count was(20.88±3.71)×109/L,which were significantly higher than(0.49±0.18)ng/ml,(5.08±0.72)mg/L and(6.04±1.25)×109/L in the reference group(P<0.05).In the severe group,the procalcitonin was(33.05±8.21)ng/ml,the C-reactive protein(98.76±16.35)mg/L and the white blood cell count was(29.74±3.35)×109/L,which were significantly higher than(7.41±1.98)ng/ml,(23.04±7.82)mg/L and(12.01±2.57)×109/L in the mild group(P<0.05).The positive detection rate of procalcitonin test for respiratory infection was 96.00%,which was higher than that of C-reactive protein test(80.00% )and white blood cell count test(74.00% )(P<0.05).The difference between the positive detection rate of respiratory infection by C-reactive protein test and white blood cell count test was not statistically significant(P>0.05).After treatment,the procalcitonin of the infection group was(6.53±2.01)ng/ml,the C-reactive protein was(8.21±1.24)mg/L and the white blood cell count was(8.64±1.33)×109/L,which were significantly lower than those before treatment(P<0.05).After treatment,the procalcitonin,C-reactive protein and white blood cell count in both the mild group and severe group were lower than those before treatment(P<0.05).Conclusion Testing procalcitonin in patients with respiratory infection can not only confirm the diagnosis of infection,but also understand the degree of infection,which can provide a reference for treatment,and evaluate the prognosis.
ProcalcitoninRespiratory infectionDiagnostic value
万方数据
维普
