Correlation analysis between serum CK-MB levels and severity of acute myocardial infarction in patients
Objective To study the correlation between serum creatine kinase isoenzyme(CK-MB)levels and severity of acute myocardial infarction(AMI)in patients.Methods A total of 98 AMI patients was collected for retrospective analysis,and they were divided into a heavier group and a lighter group according to the severity of the disease,with 35 and 63 cases,respectively.The clinical data[age,gender,smoking history,low-density lipoprotein(LDL-C),high-density lipoprotein(HDL-C),heart rate(HR),cardiac troponin(cTnI),heart type fatty acid binding protein(H-FABP),CK-MB]were compared between the two groups,and Logistic regression analysis was done to analyze factors influencing the severity of AMI patients.Results There were no significant differences in age,gender,smoking history,LDL-C,HDL-C and HR between the two groups(P>0.05).The cTnI,H-FABP and CK-MB were(25.62±5.24),(122.18±20.65)and(64.08±12.17)ng/ml in the heavier group,which were higher than(16.41±4.28),(56.57±23.12)and(25.94±18.54)ng/ml in the lighter group,and the differences were significant(P<0.05).Logistic regression analysis showed that cTnI and H-FABP were not independent factors influencing the severity of AMI(OR=1.373,1.652;P>0.05),CK-MB was an independent factor affecting the severity of AMI(OR=2.186,P<0.05).Conclusion The serum CK-MB level is closely related to the severity of AMI patients,and excessive CK-MB is an independent risk factor for the severity of AMI.
Creatine kinase isoenzymeAcute myocardial infarctionSeverity of the conditionCorrelation
万方数据
维普
