Effect of linagliptin tablets combined with Huangkui capsules on CysC and Hcy of patients with early diabetic nephropathy
Objective To observe the effect of linagliptin tablets combined with Huangkui capsules on cystatin C(CysC)and homocysteine(Hcy)of patients with early diabetic nephropathy.Methods The clinical data of 70 patients with early diabetic nephropathy were retrospectively collected and divided into a control group and a study group according to different treatment regimens,with 35 cases in each group.The control group was treated with linagliptin tablets,and the study group was treated with linagliptin tablets combined with Huangkui capsules.The changes of CysC and Hcy levels before and after treatment were compared between the two groups.Results After treatment,the study group had CysC of(1.14±0.23)mg/L and Hcy of(9.25±1.75)μmol/L,which were significantly lower than(1.82±0.63)mg/L and(12.84±2.26)μmol/L in the control group,and the difference was statistically significant(P<0.05).Conclusion Linagliptin tablets combined with Huangkui capsules for early diabetic nephropathy patients can effectively reduce the levels of CysC and Hcy and improve the therapeutic effect.
Early diabetic nephropathyLinagliptin tabletsHuangkui capsulesCystatin CHomocysteineTreatment effect