Clinical efficacy and safety analysis of Xuefu Zhuyu Decoction combined with acupuncture in treating patients with unstable angina pectoris of coronary heart disease
Objective To analyze the efficacy of Xuefu Zhuyu Decoction combined with acupuncture on patients with unstable angina pectoris of coronary heart disease,and its influence on patients'cardiac function indicators,angina pectoris attack and the incidence of adverse reactions during treatment.Methods 108 patients with unstable angina pectoris of coronary heart disease were divided into a control group(54 cases)and a study group(54 cases)at a 1‥1 ratio.Both groups were treated with conventional drugs according to coronary heart disease guidelines,and the study group was treated with Xuefu Zhuyu Decoction combined with acupuncture.Both groups were compared in terms of clinical efficacy,cardiac function indicators[left ventricular end-diastolic volume(LVEDV),left ventricular end-systolic volume(LVESV),left ventricular ejection fraction(LVEF)],angina pectoris attack(duration of angina attack,frequency of angina attack)before and after treatment and adverse reactions.Results The total clinical effective rate of the study group was 96.30%,which was higher than 85.19% of the control group(P<0.05).After treatment,LVEDV and LVESV decreased and LVEF increased in both groups compared with those before treatment;the study group had LVEDV of(159.72±16.58)ml and LVESV of(92.51±10.07)ml,which were smaller than(174.61±16.76)and(102.61±10.83)ml in the control group;LVEF of(59.28±6.02)% in the study group was higher than(56.12±5.74)% in the control group(P<0.05).After treatment,the duration of angina attacks was shorter and the frequency of angina attacks was less in both groups compared with those before treatment;the duration of angina attack of(1.16±0.17)min in the study group was shorter than(3.04±0.54)min in the control group,and the frequency of angina attack of(1.57±0.34)times/week was less than(3.67±1.02)times/week in the control group(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups during treatment(P>0.05).Conclusion The combination of Xuefu Zhuyu Decoction with acupuncture can enhance the clinical efficacy of patients with unstable angina of coronary heart disease,improve cardiac function,and reduce angina pectoris attack without increasing the adverse reactions of the patients.So this regimen is a more optimal regimen for the treatment of patients with unstable angina of coronary heart disease.
万方数据
维普
