Analysis of therapeutic effect of exercise therapy combined with acupoint application on knee osteoarthritis
Objective To analyze the therapeutic effect of exercise therapy combined with acupoint application on knee osteoarthritis.Methods A retrospective selection was conducted on 70 patients with knee osteoarthritis.According to different intervention method,they were divided into a combined intervention group and a conventional intervention group,with 35 cases in each group.The conventional intervention group was treated with celecoxib capsule,and the combined intervention group was treated with exercise therapy combined with acupoint application.Both groups were compared in terms of traditional Chinese medicine syndrome score,knee symptom score,knee range of motion,knee joint function,inflammatory indicators,bone metabolic markers,muscle function recovery,quality of life and clinical efficacy.Results After the intervention,the scores of joint pain,joint swelling,lower back and knee soreness,poor flexion and extension,limited mobility,spontaneous sweating and night sweating,and fatigue in both groups were all lower than those before the intervention,and the combined intervention group was lower than the conventional intervention group(P<0.05).After the intervention,the Western Ontario and McMaster University Osteoarthritis Index(WOMAC)for morning stiffness,pain,daily activity,total WOMAC score and knee range of motion in both groups were all better than those before the intervention;in the combined intervention group,the morning stiffness score was(2.74±0.47)points,the pain score was(5.41±1.47)points,the daily activity score was(30.11±5.13)points,the total WOMAC score was(38.26±3.30)points and the knee range of motion was(75.53±2.96)°,which were better than(3.83±1.26)points,(8.77±1.85)points,(37.72±5.03)points,(50.32±7.72)points and(58.63±1.5)° in the conventional intervention group(P<0.05).After the intervention,the HSS score in both groups was higher than that before the intervention,and the HSS score of(72.63±8.43)points in the combined intervention group was higher than(65.34±7.85)points in the conventional intervention group(P<0.05).After the intervention,the hypersensitive C-reactive protein(hs-CRP),superoxide dismutase(SOD),tumor necrosis factor-α(TNF-α),interleukin-1β,IL-6,IL-10 and IL-17 in both groups were superior to those before intervention,and the combined intervention group was superior to the conventional intervention group(P<0.05).After the intervention,the levels of osteocalcin(BGP),25-hydroxyvitamin D3(25-OH-D3),bone alkaline phosphatase(BALP)and tartrate-resistant acid phosphatase 5b(TRACP-5b)in both groups were better than those before the intervention,and the combined intervention group was better than the conventional intervention group(P<0.05).After the intervention,the score of short musculoskeletal function assessment(SMFA)in both groups were lower than those before the intervention;the score of SMFA of(23.12±3.63)points in the combined intervention group was lower than(35.08±4.02)points in the conventional intervention group(P<0.05).After the intervention,the Arthritis Impact Measurement Scales 2(AIMS2)for body,symptom,impact,social,job and total AIMS2 score in both groups were higher than those before the intervention,and the combined intervention group was higher than the conventional intervention group(P<0.05).The excellent rate of the combined intervention group was 97.14%(34/35),which was higher than 77.14%(27/35)of the conventional intervention group(P<0.05).Conclusion The combination of exercise therapy and acupoint application in the intervention of knee osteoarthritis has a better effect on functional recovery than conventional intervention.
Knee osteoarthritisExercise therapyAcupoint applicationFunctional recoveryQuality of life
万方数据
维普
