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儿童哮喘控制现状及其影响因素分析

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目的 探讨儿童哮喘控制现状及其影响因素。方法 选择 158 例哮喘患儿作为研究对象,根据哮喘控制测试(ACT)评分不同将患儿分为完全控制组(ACT评分>19分,107例)和控制不良组(ACT评分≤19 分,51 例)。采用自制的临床资料问卷调查表对患儿及其监护人进行调查(性别、年龄、病程、肥胖情况、主要照顾者、监护人吸烟、疾病严重程度、吸入糖皮质类固醇治疗依从性、健康教育、体育锻炼、饮食支持、规律随诊、合并变应性鼻炎),分析哮喘控制效果的影响因素。结果 控制不良组患儿年龄 4~6 岁、监护人吸烟、疾病严重程度为中度、吸入糖皮质类固醇治疗无依从性、无健康教育、无体育锻炼、无饮食支持、无规律随诊、合并变应性鼻炎占比分别为 47。06%(24/51)、33。33%(17/51)、74。51%(38/51)、56。86%(29/51)、58。82%(30/51)、50。98%(26/51)、43。14%(22/51)、39。22%(20/51)、60。78%(31/51),与完全控制组的 23。36%(25/107)、14。95%(16/107)、55。14%(59/107)、22。43%(24/107)、20。56%(22/107)、24。30%(26/107)、15。89%(17/107)、9。35%(10/107)、41。12%(44/107)比较存在差异(χ2=9。063、7。061、5。467、18。369、22。901、11。136、13。795、20。033、5。355,P<0。05)。经多因素Logistic回归分析显示,年龄小[OR=1。343,95%CI=(1。025,1。835)]、监护人吸烟[OR=1。294,95%CI=(1。012,1。903)]、疾病严重程度高[OR=1。373,95%CI=(1。029,1。876)]、吸入糖皮质类固醇治疗无依从性[OR=1。402,95%CI=(1。101,1。932)]、无健康教育[OR=1。334,95%CI=(1。022,1。927)]、无体育锻炼[OR=1。408,95%CI=(1。106,1。886)]、无饮食支持[OR=1。361,95%CI=(1。029,1。871)]、无规律随诊[OR=1。365,95%CI=(1。031,1。799)]、合并变应性鼻炎[OR=1。320,95%CI=(1。025,1。835)]是哮喘控制不良的独立危险因素(P<0。05)。结论 儿童哮喘控制效果仍然不佳,导致哮喘控制不良的因素较为复杂,应针对影响因素做好体育锻炼、健康教育、饮食支持、规律随诊及积极治疗变应性鼻炎,进而提高儿童哮喘控制水平。
Analysis of current status and influencing factors of asthma control in children
Objective To explore the current status and influencing factors of asthma control in children.Methods A total of 158 children with asthma were selected as the study subjects,and the children were categorized into the fully controlled group[asthma control test(ACT)score>19 points,107 cases)and the poorly controlled group(ACT score≤19 points,51 cases)according to different ACT score.A self-administered clinical data questionnaire was used to survey the children and their guardians(gender,age,duration of disease,obesity status,primary caregiver,smoking by guardians,disease severity,adherence to inhaled glucocorticosteroid therapy,health education,physical activity,dietary support,regular follow-up,and comorbid allergic rhinitis)to analyze the influencing factors affecting the outcome of asthma control.Results In the poorly controlled group,the percentages of children aged 4-6 years,smoking guardian,moderate disease severity,non-compliance with inhaled glucocorticosteroid therapy,no health education,no physical exercise,no dietary support,no regular follow-up,and comorbid allergic rhinitis were 47.06%(24/51),33.33%(17/51),74.51%(38/51),56.86%(29/51),58.82%(30/51),50.98%(26/51),43.14%(22/51),39.22%(20/51),and 60.78%(31/51);in the fully controlled group,they were 23.36%(25/107),14.95%(16/107),55.14%(59/107),22.43%(24/107),20.56%(22/107),24.30%(26/107),15.89%(17/107),9.35%(10/107),and 41.12%(44/107);there was a difference between the two groups(χ2=9.063,7.061,5.467,18.369,22.901,11.136,13.795,20.033,5.355;P<0.05).Multivariate Logistic regression analysis showed that young age[OR=1.343,95%CI=(1.025,1.835)],smoking guardian[OR=1.294,95%CI=(1.012,1.903)],high severty of disease[OR=1.373,95%CI=(1.029,1.876)],no adherence to inhaled glucocorticosteroid therapy[OR=1.402,95%CI=(1.101,1.932)],no health education[OR=1.334,95%CI=(1.022,1.927)],no physical activity[OR=1.408,95%CI=(1.106,1.886)],no dietary support[OR=1.361,95%CI=(1.029,1.871)],no regular follow-up[OR=1.365,95%CI=(1.031,1.799)],and comorbid allergic rhinitis[OR=1.320,95%CI=(1.025,1.835)]were the independent risk factors for poor asthma control(P<0.05).Conclusion The effect of asthma control in children is still poor,and the factors that lead to poor asthma control are complex.It is necessary to focus on the influencing factors,such as physical exercise,health education,dietary support,regular follow-up,and active treatment of allergic rhinitis,in order to improve the control of childhood asthma.

ChildrenAsthmaControl effectInfluencing factor

黄艳萍

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351100 莆田市儿童医院儿内二科

儿童 哮喘 控制效果 影响因素

2024

中国现代药物应用
中国水利电力医学科学技术学会

中国现代药物应用

影响因子:0.862
ISSN:1673-9523
年,卷(期):2024.18(17)