The predictive value of transthoracic echocardiography combined with contrast-enhanced ultrasound in detection of coronary flow reserve for coronary artery disease in hypertensive patients
Objective To explore the predictive value of transthoracic echocardiography combined with contrast-enhanced ultrasound in detection of coronary flow reserve(CFR)for coronary artery disease in hypertensive patients.Methods 45 patients with hypertension accompanied by left ventricular hypertrophy were included in the observation group,and another 45 patients with simple hypertension were included in the control group.Transthoracic echocardiography combined with contra-enhanced ultrasound was performed in patients to compare the transthoracic echocardiographic findings and contrast-enhanced findings between the two groups.Results There was no difference in resting peak diastolic velocity(PDV)between the two groups(P>0.05).The observation group had load PDV of(47.34±14.98)cm/s and CFR of(1.94±0.78),which were lower than(67.78±15.57)cm/s and(2.83±1.82)of the control group(P<0.05).In the observation group,the perfusion volume was(7.02±2.91)L/min,the peak curve intensity was(9.46±7.62)dB,and the curve slope was(1.23±1.03)dB/s,which were lower than(9.64±3.34)L/min,(16.78±8.43)dB,and(1.78±1.22)dB/s in the control group;the positive rate of perfusion of 71.11%was higher than 22.22%in the control group(P<0.05).Conclusion Transthoracic echocardiography combined with contrast-enhanced ultrasound can realize the evaluation of CFR,help to understand the coronary artery disease in hypertensive patients,and provide evidence for the prevention and treatment of coronary artery disease.
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