中国现代药物应用2024,Vol.18Issue(17) :95-97.DOI:10.14164/j.cnki.cn11-5581/r.2024.17.025

阿托伐他汀钙片联合参芎葡萄糖注射液治疗缺血性脑血管病的临床效果观察

Clinical observation of atorvastatin calcium tablets combined with Shenxiong glucose injection in the treatment of ischemic cerebrovascular disease

张升粮 黄富城 邹小燕
中国现代药物应用2024,Vol.18Issue(17) :95-97.DOI:10.14164/j.cnki.cn11-5581/r.2024.17.025

阿托伐他汀钙片联合参芎葡萄糖注射液治疗缺血性脑血管病的临床效果观察

Clinical observation of atorvastatin calcium tablets combined with Shenxiong glucose injection in the treatment of ischemic cerebrovascular disease

张升粮 1黄富城 1邹小燕1
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作者信息

  • 1. 341600 信丰县妇幼保健院内科
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摘要

目的 研究阿托伐他汀钙片联合参芎葡萄糖注射液治疗缺血性脑血管病的临床效果.方法 选择64例缺血性脑血管病患者作为本次研究案例,运用计算机数字表法分为参照组(32例,使用阿托伐他汀钙片治疗)和研讨组(32例,使用阿托伐他汀钙片联合参芎葡萄糖注射液治疗).比较两组患者用药前后血脂水平,药物安全性,用药前后肢体功能评分.结果 用药 0.5 个月后,研讨组患者的甘油三酯(1.02±0.29)mmol/L、低密度脂蛋白胆固醇(1.53±0.34)mmol/L、总胆固醇(2.15±0.71)mmol/L均低于参照组的(1.54±0.31)、(2.42±0.79)、(3.65±0.98)mmol/L,高密度脂蛋白胆固醇(1.58±0.65)mmol/L高于参照组的(1.23±0.54)mmol/L,组间比较差异具统计学意义(P<0.05).用药期间研讨组患者的不良反应发生率 3.13%低于参照组患者的 21.88%,组间比较差异具统计学意义(P<0.05).用药 0.5 个月后,研讨组患者的肢体功能评分(88.01±7.74)分高于参照组的(71.62±6.29)分,组间比较差异具统计学意义(P<0.05).结论 阿托伐他汀钙片联合参芎葡萄糖注射液治疗缺血性脑血管病的临床效果明显,可良好改善患者的血脂水平,且安全性高,具有较高的应用价值.

Abstract

Objective To study the clinical effect of atorvastatin calcium tablets combined with Shenxiong glucose injection in the treatment of ischemic cerebrovascular disease.Methods 64 patients with ischemic cerebrovascular disease were selected as the study cases and divided into a reference group(32 cases,treated with atorvastatin calcium tablets)and a study group(32 cases,treated with atorvastatin calcium tablets combined with Shenxiong glucose injection)by computer digital table method.The blood lipid level,drug safety and limb function score before and after medication were compared between the two groups.Results After 0.5 months of medication,the study group had triglycerides of(1.02±0.29)mmol/L,low-density lipoprotein cholesterol of(1.53±0.34)mmol/L,and total cholesterol of(2.15±0.71)mmol/L,which were lower than(1.54±0.31),(2.42±0.79),and(3.65±0.98)mmol/L in the reference group;the high density lipoprotein cholesterol of(1.58±0.65)mmol/L in the study group was higher than(1.23±0.54)mmol/L in the reference group;the difference between groups was statistically significant(P<0.05).During the medication,the incidence rate of adverse reactions in the study group was 3.13%,which was lower than 21.88%in the reference group,and the difference between groups was statistically significant(P<0.05).After 0.5 months of medication,the limb function score of the patients in the study group was(88.01±7.74)points,which was higher than(71.62±6.29)points in the reference group,and the difference between groups was statistically significant(P<0.05).Conclusion The combination of atorvastatin calcium tablet and Shenxiong glucose injection has significant effect in the treatment of ischemic cerebrovascular disease,and it can improve the patients'lipid level well.It has high safety and high application value.

关键词

阿托伐他汀钙片/参芎葡萄糖注射液/缺血性脑血管病/血脂

Key words

Atorvastatin calcium tablets/Shenxiong glucose injection/Ischemic cerebrovascular disease/Blood lipid

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出版年

2024
中国现代药物应用
中国水利电力医学科学技术学会

中国现代药物应用

影响因子:0.862
ISSN:1673-9523
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