Application effect of propofol intravenous anesthesia combined with combined spinal-epidural anesthesia in hip fracture surgery
Objective To analyze the effectiveness of propofol intravenous anesthesia combined with combined spinal-epidural anesthesia in hip fracture surgery.Methods 72 patients with hip fracture surgery were divided into an observation group and a control group according to coin-tossing method,with 36 patients in each group.The control group received combined spinal-epidural anesthesia,and the observation group received propofol intravenous anesthesia combined with combined spinal-epidural anesthesia.The pain score at 12 h after surgery,anesthesia effect,hemodynamic index and cognitive function were compared between the two groups.Results 12 h after surgery,the pain score of(1.92±0.21)points in the observation group was lower than(2.46±0.23)points in the control group(P＜0.05).The excellent rate of anesthesia of 100.00% in the observation group was higher than 86.11% in control group(P＜0.05).There were no significant differences in heart rate before anesthesia induction and extubation at the end of surgery and blood oxygen saturation before anesthesia induction between the two groups(P＞0.05).The heart rate of the observation group were(69.38±5.12)and(67.27±5.23)beats/min at 5 and 30 min of anesthesia,which were lower than(72.46±7.12)and(70.31±4.82)beats/min of the control group(P＜0.05);the blood oxygen saturation of the observation group were(97.38±0.28)%,(98.32±0.28)% and(97.56±0.11)% at 5 and 30 min of anesthesia,extubation at the end of surgery,which were higher than(95.77±0.25)%,(96.00±0.31)% and(95.64±0.54)% of the control group(P＜0.05).There was no significant difference in the score of the Mini-Mental State Examination(MMSE)at 1 d before surgery between the two groups(P＞0.05).The MMSE scores of the observation group were(24.11±1.33),(26.88±1.21)and(28.31±0.98)points at 1 d,3 d and 1 week after surgery,which were higher than(22.73±1.21),(24.33±1.37)and(27.38±1.72)points of the control group(P＜0.05).Conclusion Propofol intravenous anesthesia combined with combined spinal-epidural anesthesia is effective in hip fracture surgery,which is conducive to reducing postoperative pain,stabilizing hemodynamic index,and improving cognitive function of patients,and is worth promoting.
Hip fracture surgeryPropofolIntravenous anesthesiaCombined spinal-epidural anesthesia
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