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瘀血痹片在骨折术后肢体肿胀中的应用效果观察

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目的 探究瘀血痹片在骨折术后肢体肿胀中的应用效果。方法 选择 110 例骨折术后肢体肿胀患者作为研究对象,并基于随机数字表法将患者分为对照组与观察组,各 55 例。对照组患者给予五松肿痛酊治疗,观察组患者给予五松肿痛酊+瘀血痹片治疗。比较两组患者的治疗效果、肿胀程度改善情况、疼痛评分、炎性水平。结果 观察组患者治疗总有效率 98。19%明显高于对照组的81。82%,具有显著性统计学差异(P<0。05)。观察组患者治疗后大腿、小腿的直径差分别是(0。52±0。14)、(0。73±0。26)cm,均明显小于对照组的(1。08±0。42)、(1。56±0。52)cm,具有显著性统计学差异(P<0。05)。治疗后,两组患者疼痛评分均明显低于本组治疗前,且观察组患者疼痛评分(1。84±0。23)分明显低于对照组的(4。05±1。14)分,具有显著性统计学差异(P<0。05)。观察组患者治疗后白细胞介素-6(IL-6)(4。26±1。22)pg/ml、C反应蛋白(CRP)(4。01±1。25)mg/L、肿瘤坏死因子-α(TNF-α)(1。14±0。16)ng/ml均明显低于对照组的(6。15±1。03)pg/ml、(7。22±1。64)mg/L、(1。82±0。27)ng/ml,具有显著性统计学差异(P<0。05)。结论 在骨折术后肢体肿胀治疗中,瘀血痹片治疗效果显著,在改善肿胀、炎性程度的同时,能有效提高治疗总有效率,值得推广应用。
Observation on the application effect of Yuxuebi tablets in postoperative limb swelling after fracture surgery
Objective To explore the application effect of Yuxuebi tablets in postoperative limb swelling after fracture surgery.Methods 110 patients with postoperative limb swelling after fracture surgery were selected as the research subjects.Based on the random number table method,the patients were divided into a control group and an observation group,each consisting of 55 cases.The control group was treated with Wusong Zhongtong Tincture,while the observation group was treated with Wusong Zhongtong Tincture and Yuxuebi tablets.The treatment effect,swelling improvement,pain score,inflammation level of the two groups were compared.Results The total effective rate of the observation group was 98.19%,which was significantly higher than 81.82% of the control group,and there was statistically significant difference(P<0.05).After treatment,the diameter differences of the thighs and calves in the observation group were(0.52±0.14)and(0.73±0.26)cm,which were significantly smaller than(1.08±0.42)and(1.56±0.52)cm in the control group,and there was statistically significant difference(P<0.05).After treatment,the pain score of the two groups was significantly lower than that before treatment,and the pain score of(1.84±0.23)points of the observation group was significantly lower than(4.05±1.14)points of the control group;there was statistically significant difference(P<0.05).After treatment,the observation group had interleukin-6(IL-6)of(4.26±1.22)pg/ml,C-reactive protein(CRP)of(4.01±1.25)mg/L,and tumor necrosis factor-α(TNF-α)of(1.14±0.16)ng/ml,which were significantly lower than(6.15±1.03)pg/ml,(7.22±1.64)mg/L and(1.82±0.27)ng/ml in the control group,and there was statistically significant difference(P<0.05).Conclusion In the treatment of limb swelling of postoperative fractures,Yuxuebi tablets show a significant therapeutic effect,which can improve the degree of swelling and inflammation while effectively improving the treatment efficiency.It is worth promoting and applying.

FracturesYuxuebi tabletsPostoperative limb swellingWusong Zhongtong Tincture

李建龙

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510515 南方医科大学南方医院关节与骨病外科

骨折 瘀血痹片 术后肢体肿胀 五松肿痛酊

2024

中国现代药物应用
中国水利电力医学科学技术学会

中国现代药物应用

影响因子:0.862
ISSN:1673-9523
年,卷(期):2024.18(18)