Exploring the value of color Doppler ultrasonography in assessing hemodynamic changes and pregnancy outcome in pregnant women with late-onset intrauterine growth restriction
Objective To explore the value of color Doppler ultrasonography in assessing hemodynamic changes and pregnancy outcome in pregnant women with late-onset intrauterine growth restriction.Methods Among 169 pregnant women in the late stage-pregnancy who underwent prenatal examination and gave birth,78 pregnant women with normal intrauterine fetal development served as the control group,and 91 pregnant women with late-onset intrauterine growth restriction served as the case group.Color Doppler ultrasound monitoring was performed in both groups to compare pregnancy outcomes of the two groups,including fetal body weight,preterm birth and Apgar score(>7 points,≤7 points);the changes in hemodynamic parameters[pulsatility index(PI),resistance index(RI),and peak systolic flow height to end diastolic flow height ratio(S/D)and early diastolic notch]of the uterine artery,fetal umbilical artery,and middle cerebral artery between the two groups;and the changes in hemodynamic parameters of the uterine artery,fetal umbilical artery,and middle cerebral artery of pregnant women with different pregnancy outcomes in the case group.Results The fetal body mass of(2417.0±369.8)g in the case group was smaller than(3126.0±431.5)g in the control group;the percentage of preterm labor and neonatal 1-min Apgar score≤7 points were 51.65%and 47.25%,which were higher than 14.10%and 8.97%in the control group;the difference was statistically significant(P<0.05).In the case group,fetal umbilical artery RI,PI and S/D were(0.83±0.15),(1.30±0.32)and(3.81±0.42),which were significantly higher than(0.71±0.16),(0.89±0.27)and(3.24±0.31)in the control group;the maternal uterine artery PI was(1.35±0.30)and the incidence of early diastolic notching was 31.87%,which were significantly higher than(0.92±0.26)and 10.26%in the control group;the fetal middle cerebral artery RI,PI and S/D were(0.60±0.20),(1.19±0.19)and(2.51±0.31),which were significantly lower than(0.89±0.23),(1.71±0.29)and(4.19±0.27)in the control group(P<0.05).42 cases had good pregnancy outcomes and 49 cases had poor pregnancy outcomes in the case group.The umbilical artery RI,PI and S/D were(0.89±0.23),(1.35±0.26)and(4.02±0.39)in fetuses with poor gestational outcome,which were significantly higher than(0.75±0.12),(1.24±0.19)and(3.57±0.26)in fetuses with good gestational outcome;the maternal uterine artery PI was(1.56±0.31)and the incidence of early diastolic notching was 38.78%,which were significantly higher than(1.11±0.16)and 23.81%of fetuses with good pregnancy outcome;middle cerebral artery RI,PI and S/D were(0.52±0.13),(1.01±0.14)and(2.39±0.28),which were significantly lower than(0.69±0.15),(1.41±0.21)and(2.65±0.17)of fetuses with good pregnancy outcome(P<0.05).Conclusion Color Doppler ultrasonography monitoring of hemodynamic parameters of maternal uterine arteries and fetal umbilical and middle cerebral arteries during late pregnancy is an important reference in assessing fetal status in utero and predicting adverse outcomes.
万方数据
维普
