Analysis of clinical effect of emergency medical treatment of severe heart failure in the elderly
Objective To explore the clinical effect of emergency medical treatment of severe heart failure in the elderly.Methods A total of 106 elderly patients with severe heart failure were randomly divided into an experimental group and a control group,with 53 cases in each group.Patients in both groups received conventional medical treatment,on this basis,the control group received metoprolol,and experimental group received irbesartan and hydrochlorothiazide on the basis of the control group.Comparison was made on cardiac function indexes[left ventricular ejection fraction(LVEF),cardiac output(CO),B-type natriuretic peptide(BNP),heart fatty acid-binding protein(hFABP)]and clinical efficacy between the two groups.Results After treatment,LVEF and CO of the experimental group were(45.68±4.02)%and(4.23±0.38)L/min,and those of the control group were(39.25±4.15)%and(3.52±0.42)L/min.After treatment,LVEF and CO in both groups were higher than those before treatment,and LVEF and CO in the experimental group were significantly higher than those in the control group(P<0.05).After treatment,BNP and hFABP of the experimental group were(721.67±90.78)pg/ml and(10.72±2.57)ng/L,and those of the control group were(895.61±101.53)pg/ml and(13.61±3.21)ng/L.After treatment,BNP and hFABP in both groups were significantly decreased compared with those before treatment,and BNP and hFABP in the experimental group were significantly lower than those in the control group(P<0.05).The total effective rate of the experimental group(94.3%)was significantly higher than that of the control group(69.8%)(P<0.05).Conclusion Metoprolol combined with irbesartan and hydrochlorothiazide can significantly improve cardiac function and quality of life in elderly patients with severe heart failure,and has clinical value.
Severe heart failure in the elderlyEmergency internal medicineMetoprololIrbesartan and hydrochlorothiazide
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