Analysis of clinical effect of hyperosmolar glucose injection in the treatment of filamentous keratitis
Objective To observe the clinical effect of hyperosmolar glucose injection in the treatment of filamentous keratitis. Methods 70 cases of filamentous keratitis were randomly divided into an observation group and a control group,each consisting of 35 cases. The control group was treated with diclofenac eye drops and sodium diquafosol eye drops removing corneal filaments,while also receiving symptomatic treatment. The observation group was treated with hyperosmolar glucose injection based on the control group. The therapeutic effect,fluorescein break up time (FBUT) before and after treatment,and recurrence were compared between the two groups. Results In the control group,FBUT was (4.44±2.84) s before treatment and (8.08±2.32) s after 1 month of treatment;in the observation group,FBUT was (4.15±3.05) s before treatment and (8.28±2.28) s after 1 month of treatment. There was no significant difference in FBUT between the two groups before and after treatment (P>0.05). After 1 month of treatment,FBUT in both groups was longer than that before treatment,and the difference was statistically significant (P<0.05). There was no significant difference in total effective rate betweenthe two groups (P>0.05). After 2 months of treatment,the recurrence rate of 2.86％ in the observation group was lower than 17.14％ in the control group,and the difference was statistically significant (P<0.05). Conclusion Hyperosmolar glucose injection is effective in preventing short-term recurrence of filamentous keratitis,but has no significant effect on prolonging FBUT.
Hyperosmolar glucose injectionFilamentous keratitisRecurrenceFluorescein break up time
万方数据
维普
